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Polymorphism: in the Pharmaceutical Industry
Rolf Hilfiker (Editor)
ISBN: 978-3-527-31146-0
Hardcover
433 pages
April 2006
US $215.00 Add to Cart

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  • Description
  • Table of Contents
  • Author Information
  • Reviews
Preface.

List of Contributors.

1. Relevance of Solid-state Properties for Pharmaceutical Products (R. Hilfiker, et al.).

2. Thermodynamics of Polymorphs (S. Lohani & D. Grant).

3. Characterization of Polymorphic Systems Using Thermal Analysis (.D. Craig).

4. Solid-State N MR Spectroscopy (J. Lubach & E. Munson).

5. Vibrational Spectroscopic Methods in Pharmaceutical Solid-State Characterization (J. Chalmers & G. Dent).

6. Crystallography for Polymorphs (P. Ochsenbein & K. Schenk).

7. Light Microscopy (G. Nichols).

8. The Importance of Solvates (U. Griesser).

9. Physical Characterization Hygroscopicity in Pharmaceutical Solids (S. Reutzel-Eden & A. Newman).

10. The Amorphous State (S. Petit & G. Coquerel).

11. Approaches to Polymorphism Screening (R.  Hilfiker, et al.).

12. Salt Selection (P. Stahl & B. Sutter).

13. Processing-induced Phase Transformations and Their Implications on Pharmaceutical Product Quality (R. Govindarajan & R. Suryanarayanan).

14. Polymorphism and Patents from a Chemist's Point of View (J. Bernstein).

15. Scientific Considerations of Pharmaceutical Solid Polymorphism in Regulatory Applications (S. Miller, et al.).

Subject Index.