Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology
Following an introduction by Kai Simons, the discoverer of lipid rafts and the most prominent scientist in the field, chapters include:
Distinct structures and functions
Viral entry and virion budding
Cell polarity and intracellular trafficking
Of prime importance to molecular and cell biologists, biochemists, membrane scientists, cancer researchers, and virologists.
The Forces that Shape Caveolae
The Biophysical Characterization of Lipid Rafts
The Role of Caveolae and Noncaveolar Rafts in Endocytosis
Role of Cholesterol in Signal Transduction from Caveolae
Phosphorylation of Caveolin and Signaling from Caveolae
Role of Lipid Microdomains in the Formation of Supramolecular Protein Complexes and Transmembrane Signaling
Caveolin and its Role in Intracellular Chaperone Complexes
The Roles of Caveolae and Caveolin in Cell Shape, Locomotion, and Stress Fiber Formation
Lipid Rafts in Trafficking and Processing of Prion Protein and Amyloid Precursor Protein
Caveolae and the Endothelial Nitric Oxide Synthase
The Role of Caveolin-1 in Tumor Cell Survival and Cancer Progression
Professor Fielding's main research interest is in the trafficking of cholesterol, its regulation and its role in signal transduction.
Natural Cell Biology
"This is a book that will be useful to everyone interested in membrane biophysics. The chapters highlight the many unanswered questions in the field and detail some work that should be done in the future. Perhaps this book will stimulate more of us to get involved in the development of novel experimental methods and to continue trying to answer the critical unanswered questions." ChemBioChem
"... a timely summary of our current picture of the raft concept ... clarifies some misunderstood ideas."
"In conclusion, this book is a delightful mix of structural biology, biophysics, cell biology, biochemistry, physiology and medicine. All researchers in biomedicine with an interest in membrane biology will find this book both informative and an excellent point of reference. Its acquisition would provide a valuable addition to the bookshelves of all who purchase it."
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Lipid Rafts and Caveolae: From Membrane Biophysics to Cell Biology (US $245.00)
-and- Student Companion to Accompany Fundamentals of Biochemistry, 4th Edition (US $102.95)
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