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Nanomaterials for Medical Diagnosis and Therapy

ISBN: 978-3-527-31390-7
757 pages
April 2007
Nanomaterials for Medical Diagnosis and Therapy (3527313907) cover image


Following an overview of nanotechnologies for diagnostic purposes, this book goes on to look at nanoparticle-based magnetic resonance, molecular and other imaging applications, as well as the potential roles of carbon nanotubes and bionanoparticles in biomedical applications. The book's main focus is on drug delivery systems based on nonporous and nanosize materials, solid lipid and polymeric nanoparticles, intelligent hydrogels, core-shell nanoparticles, and nanocapsules, rounded off by a discussion of their biomedical applications. The final part of this volume covers such biomedical strategies as gene therapy, synthetic gene-transfer vectors and targeted delivery.
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Table of Contents

Chapter 1: Nanotechnologies for Diagnosis -
Present and Future
Chapter 2: Superparamagnetic Nanoparticles of Iron Oxides for Magnetic Resonance Imaging Applications
Chapter 3: Carbon Nanotube-based Vectors for Delivering Immunotherapeutics and Drugs
Chapter 4: Core-Shell Nanoparticles for Drug Delivery and Molecular Imaging
Chapter 5: Nanotechnologies for Targeted Delivery of Drugs
Chapter 6: Nanoporous and Nanosize Materials for Drug Delivery Systems
Chapter 7: NANOEGGTM Technology for Drug Delivery
Chapter 8: Polymeric Nanomaterials -
Synthesis, Functionalization and Applications in Diagnosis and Therapy
Chapter 9: Polymeric Nanoparticles for Drug Delivery
Chapter 10: Solid Lipid and Polymeric Nanoparticles for Drug Delivery
Chapter 11: Intelligent Hydrogels in Nanoscale Sensing and Drug Delivery Applications
Chapter 12: Nanoshells for Drug Delivery
Chapter 13: Bionanoparticles and their Biomedical Applications
Chapter 14: Nanotechnology for Gene Therapy -
HVJ-E Vector
Chapter 15: Nanotoxicology of Synthetic Gene Transfer Vectors: Poly(ethyleneimine)- and Polyfectin-mediated Membrane Damage and Apoptosis in Human Cell Lines
Chapter 16: Nanoparticles for the Treatment of Alzheimer's Disease: Theoretical Rationale, Present Status and Future Perspectives
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Author Information

Challa Kumar is currently the Group Leader of Nanofabrication at the Center for Advanced Microstructures and Devices (CAMD), Baton Rouge, USA. His research interests are in developing novel synthetic methods for functional nanomaterials and innovative therapeutic, diagnostic and sensory tools based on nanotechnology. He has eight years of industrial R&D experience working for Imperial Chemical Industries and United Breweries prior to joining CAMD. He is the founding Editor-in-Chief of the Journal of Biomedical Nanotechnology, an international peer reviewed journal published by American Scientific Publishers, and the series editor for the ten-volume book series Nanotechnologies for the Life Sciences (NtLS) published by Wiley-VCH. He worked at the Max Planck Institute for Biochemistry in Munich, Germany, as a post doctoral fellow and at the Max Planck Institute for Carbon Research in Mülheim, Germany, as an invited scientist. He obtained his Ph.D. degree in synthetic organic chemistry from Sri Sathya Sai Institute of Higher Learning, Prashanti Nilayam, India.
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"... NtLS is essential reading for all scientists working in this field from medicine and biology through chemistry, material science and physics to engineering. ..."
Anticancer Research

"Solche und ähnliche Modelle sind zwar erst Technik von übermorgen, die Leistung die 'Nanomaterials' aber hier vollbringt, ist, erstmals alle Bestrebungen auf diesem Feld gesammelt wiederzugeben."
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