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Neural Degeneration and Repair: Gene Expression Profiling, Proteomics and Systems Biology
ISBN: 978-3-527-31707-3
Hardcover
249 pages
April 2008
US $145.00 Add to Cart

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  • Description
  • Table of Contents
  • Author Information
1. INTRODUCTION
Microarrays in Translational Neuroscience - from Laboratory to Clinical Applications

2. REACTIONS OF PERIPHERAL NERVE TO TRAUMATIC INJURY AND AXON REGENERATION
The Potential of Genomewide Expression Profiling in Models of Peripheral Nervous System Injury and Repair

Largescale Screening for Regeneration-Associated Neural Proteins and Genes

Patterns of Genetic Regulation and Target Remodelling in Response to Molecular Signals to Neurons

Microarray Analysis to Decipher Peripheral Nerve Myelination

Unravelling the Mechanism of Neuropathic Pain using cDNA Arrays

Comparison of Axotomy-induced Neuronal Gene Expression Profiles in Regenerating Peripheral Nerve and Non-regenerating CNS Fiber Tract

3. CENTRAL NERVOUS SYSTEM TRAUMA AND NEURODEGENERATION
Single Cell Gene Expression and cDNA Microarray Analysis to Study Molecular Events in TBI, Neurological Degeneration and Restoration

Gene Expression Changes Induced by Blocking or Ablation of Nogo A in Spinal Cord Injury and Brain

Microarray Hybridization to Search for Genes Involved in Inhibition and Promotion of Spinal Cord Regeneration

Proteomics Technology Applied to Traumatic Brain Injury: Implications for the Identification of Diagnostic Predictors and New Therapeutic Targets

Molecular Changes in Neurodegenerative Disorders and Oxidative Stress Responses in Brain Injury

Proteomics in Molecular Medicine: Applications to CNS Diseases


4. GLYCOMIC TECHNOLOGIES APPLIED TO NERVOUS SYSTEM FUNCTION

Glycomic Approaches to Analyze Neural Functions of Glacosaminoglycans and Proteoglycans

Glycoproteomics and Glycan Profiling: Implications for Nervous System Function and Repair