Preface to the First English Edition.

Symbols and Abbreviations.

Introduction and Definitions.

References.

1 Multiple Equilibria.

1.1 Diffusion.

1.2 Interaction between Macromolecules and Ligands.

1.3 Macromolecules with Identical Independent Binding Sites.

1.4 Macromolecules with Non-identical, Independent Binding Sites.

1.5 Macromolecules with Identical, Interacting Binding Sites, Cooperativity.

1.6 Non-identical, Interacting Binding Sites.

References.

2 Enzyme Kinetics.

2.1 Reaction Order.

2.2 Steady-State Kinetics and the Michaelis-Menten Equation.

2.3 Analysis of Enzyme Kinetic Data.

2.4 Reversible Enzyme Reactions.

2.5 Enzyme Inhibition.

2.6 Multi-substrate Reactions.

2.7 Derivation of Rate Equations of Complex Enzyme Mechanisms.

2.8 Kinetic Treatment of Allosteric Enzymes.

2.9 pH and Temperature Dependence of Enzymes.

2.10 Isotope Exchange.

2.11 Special Enzyme Mechanisms.

2.12 Application of Statistical Methods in Enzyme Kinetics.

References.

3 Methods.

3.1 Methods for Investigation of Multiple Equilibria.

3.2 Electrochemical Methods.

3.3 Calorimetry.

3.4 Spectroscopic Methods.

3.5 Measurement of Fast Reactions.

References.

Subject Index.