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Carbon Nanomaterials

ISBN: 978-3-527-32169-8
482 pages
March 2011
Carbon Nanomaterials (3527321691) cover image

Description

The book series Nanomaterials for the Life Sciences, provides an in-depth overview of all nanomaterial types and their uses in the life sciences.

Each volume is dedicated to a specific material class and covers fundamentals, synthesis and characterization strategies, structure-property relationships and biomedical applications. The series brings nanomaterials to the Life Scientists and life science to the Materials Scientists so that synergies are seen and developed to the fullest.

Written by international experts of various facets of this exciting field of research, the series is aimed at scientists of the following disciplines: biology, chemistry, materials science, physics, bioengineering, and medicine, together with cell biology, biomedical engineering, pharmaceutical chemistry, and toxicology, both in academia and fundamental research as well as in pharmaceutical companies.


VOLUME 9 - Carbon Nanomaterials

This volume describes Carbon Nanomaterials, from syntheses to characterization, as well as their application to the Life Sciences, Carbon Nanomaterials can be used in a variety of fields, from tissue engineering to cancer treatment.

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Table of Contents

Preface

PART I: Overview of Synthesis, Characterization, and Applications in Biomedicine

CARBON NANOMATERIALS: SYNTHETIC APPROACHES
Introduction
General Concepts on the Synthesis of Carbon (Nano-)Materials
Synthesis from Solid Precursors
Catalytic Chemical Vapor Deposition
Purification Techniques
Importance of Defects and Curvature for Further Functionalization
Functionalization: Creating Anchoring Points for Bioactive Molecules
Conclusion and Outlook
NANOCARBONS: CHARACTERIZATION TOOLS
Introduction
Diffraction Techniques
Imaging
Spectroscopy
Summary
SYNTHESIS, CHARACTERIZATION, AND BIOMEDICAL APPLICATIONS OF GRAPHENE
Introduction
Synthesis of Graphene
Characterization of Graphene
Biomedical Applications of Graphene
Conclusions
CAR$BON NANOHORNS AND THEIR BIOMEDICAL APPLICATIONS
Introduction
Structure and Properties
Functionalization
Biomedical Applications
Conclusions
BIO-INSPIRED MAGNETIC CARBON MATERIALS
Introduction
Allotropic Forms of Carbon
Magnetism in Diamond
Magnetism in Graphite
Magnetism in Carbon Nanotubes/Fullerenes
Magnetism in Graphene
Conclusion
MULTI-WALLED CARBON NANOTUBES FOR DRUG DELIVERY
Introduction
Gene Therapy
Antibacterial Therapy
Wound Healing
Chemotherapy
Summary and Future Perspectives
CARBON NANOTUBE-BASED THREE-DIMENSIONAL MATRICES FOR TISSUE ENGINEERING
Introduction
Carbon Nanotubes
Carbon Nanotubes for Matrix Enhancement
Cellular Responses to CNT-Based Matrices
CNT Engineering into Three-Dimensional Matrices
Summary
ELECTROCHEMICAL BIOSENSORS BASED ON CARBON NANOTUBES
Introduction
CNT Properties
Electrochemical Biosensing
CNT-Based Electrode Fabrication
Applications
Conclusions
SINGLE-WALLED CARBON NANOTUBE BIOSENSORS
Introduction
The Sensing Mechanism of Nanotube Biosensors
The Immobilization of Biomolecules on SWNTs
Various Receptors for Nanotube Biosensors
The Application of Nanotube Biosensors to Pathogen Detection
The Future of Nanotube Biosensors
ENVIRONMENTAL IMPACT OF FULLERENES
Introduction
Methods Used to Prepare Fullerene Suspensions
Toxicological Data Relating to Fullerene
Possible Emission Sources of C60
The Environmental Fate of C60
Fullerenes in the Environment
Conclusion
COMPUTATIONAL TOOLS FOR THE BIOMEDICAL APPLICATION OF CARBON NANOMATERIALS
Introduction
Simulation Methods
Results and Discussion
Future Perspectives
Executive Summary

PART II: Overview of Applications in Cancer

CARBON NANOTUBES FOR CANCER THERAPY
Introduction
Hyperthermia for Cancer Treatment
CNTs for Drug Delivery
Imaging Using CNTs
CNT-Related Toxicity
Summary and Future Perspective
CANCER TREATMENT WITH CARBON NANOTUBES, USING THERMAL ABLATION OR ASSOCIATION WITH ANTICANCER AGENTS
Introduction
Use of Nanotubes as Heated Particles
Use of Anticancer Agents Associated with Nanotubes
Summary
Future Perspective
CARBON NANOTUBES FOR TARGETED CANCER THERAPY
Introduction
Cancer
Conventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery
Carbon Nanotubes as Drug-Delivery Vehicles
Cellular Uptake of CNTs
Functionalization of CNTs with Polyethylene Glycol
Targeting of Cancers
Targeted Cancer Therapy Employing CNTs and a Critique of Current Studies
Summary and Future Perspective
APPLICATION OF CARBON NANOTUBES TO BRAIN TUMOR THERAPY
Introduction
The Current Challenge of Brain Tumor Therapy
The Characteristics of CNTs for Biological Applications
Strategies of Application of CNTs to Brain Tumor Therapy
Toxicity Issues of CNTs in Brain Tumor Therapy
Conclusions and Future Directions
CARBON NANOTUBES IN CANCER THERAPY, INCLUDING BORON NEUTRON CAPTURE THERAPY (BNCT)
Introduction
Carbon Nanotubes in the Treatment of Cancer
BNCT and Its Development through Nanotechnology
The Role of Carbon Nanotubes in BNCT
Summary and Future Outlook
FULLERENES IN PHOTODYNAMIC THERAPY
Introduction
Photodynamic Therapy
Fullerenes as Photosensitizers
Anticancer Effects of Fullerenes
Fullerenes for Antimicrobial Photoinactivation
Summary and Future Perspectives
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Author Information

Challa Kumar is currently the Director of Nanofabrication & Nanomaterials at the Center for Advanced Microstructures and Devicees (CAMD), Baton Rouge, USA. He is also the President and CEO of Magnano Technologies, a company established to commercialize nanomaterials for applications in life sciences. His research interests are in developing novel synthetic methods, including those based on microfluidic reactors, for multifunctional nanomaterials. He has also been involved in the development of innovative therapeutic & diagnostic tools based on nanotechnology. He has eight years of industrial R&D experience working for Imperial Chemical Industries and United Breweries. He is the founding Editor-in-Chief of the Journal of Biomedical Nanotechnology, published by American Scientific Publishers and Series editor for the ten-volume book series, Nanotechnologies for the Life Sciences (NtLS), published by Wiley-VCH.
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Reviews

"These ten volumes provide an excellent, in-depth overview of all nanomaterial types and their uses in the life sciences." (Breitbart.com: Business Wire, 17 February 2011)
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