A Statistical Approach to Genetic Epidemiology: Concepts and Applications, with an e-Learning Platform, 2nd Edition
June 2010, Wiley-Blackwell
The book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. The second edition is thoroughly revised, partly rewritten and includes now chapters on segregation analysis, twin studies and estimation of heritability. The book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics.
Like in the first edition the book contains many problems and solutions. However, it now comes with an optional e-learning course, created by Friedrich Pahlke and developed to complement the book. Both provide a unique support tool for teaching the subject.
LINKAGE ANALYSIS AND FAMILY STUDIES
Genetic Map Distances
Model Based Linkage Analysis
Model Free Linkage Analysis for Binary Traits
Model Free Linkage Analysis for Quantitative Traits
Family Studies not Involving Genetic Markers
Fundamental Concepts of Association Analyses
Association Analysis with Unrelated Individuals
Family Based Association Analysis
Inke R. König studied psychology at the universities of Marburg (Germany) as a scholar of the German National Academic Foundation and Dundee (Scotland) with a grant from the German Academic Exchange Service (DAAD). She has done research work at the Institute of Medical Biometry and Epidemiology in Marburg and since 2001 at the Institute of Medical Biometry and Statistics in Lübeck. In 2004, she became vice director of the latter and also received the Fritz-Linder-Forum-Award from the German Association for Surgery. Besides holding the certificate "Biometrics in Medicine", she has collected teaching experience since 1998 as a lecturer for biomathematics, behavioural genetics, clinical epidemiology, genetic epidemiology, and evidence-based medicine.
Friedrich Pahlke is Dipl. Inf. at the Institute for Medical Biometry and Statistics at the University Clinic Schleswig-Holstein in Lübeck. He has created the e-learning course which is optionally available with the book.
“This is a well-written, quality addition to the literature. It is an excellent resource/textbook for those wanting to teach genetic epidemiology as well as those wishing to learn the basics of genetic epidemiology. The new edition improves on the previous edition and expands on necessary topics that have grown in importance over the last five years.” (Doody’s, 4 January 2013)