Pharmacokinetics and Metabolism in Drug Design, 3rd Edition

The third edition features several new subchapters on novel approaches that are currently in the focus of pharmaceutical scientists.
In the Physicochemistry chapter, new sections on membrane systems and on the BCS classification have been added. The Absorption chapter now also discusses active transports and prodrugs for increased oral absorption.
Distribution of drugs into tumors and active metabolites are now discussed in chapters 4 and 5. The toxicity chapter has been completely rewritten to cover the current risk assessment-driven approach in the field. Chapter 9 (Inter-species scaling) has been replaced with a new chapter on the prediction of human pharmacokinetics that shows the current integrated in vitro/in vivo/in silico approach that has become the standard in the industry.
Data in figures and tables have been updated where appropriate, and new references have been added.