Bacterial and Eukaryotic Porins: Structure, Function, Mechanism
For the first time, it brings together biophysical evidence with studies performed in a cellular context, presenting a unified picture of the fundamental importance of porins for cellular function.
With 16 contributions by an interdisciplinary team of leading porin researchers, this reference is essential reading for every molecular or structural biologist with an interest in this essential protein family.
List of Contributors.
1. Regulation of Porin Gene Expression by the Two-Component Regulatory System EnvZ/OmpR (D. Walthers, et al.).
2. The Structures of General Porins (G. Schulz).
3. Role of Bacterial Porins in Antibiotic Susceptibility of Gram-negative Bacteria (J. Pagés).
4. Porins of the Outer Membrane of Pseudomonas aeruginosa (R. Hancock & S. Tamber).
5. Regulation of Bacterial Porin Function (A. Baslé & A. Delcour).
6. Reconstitution of General Diffusion Pores from Bacterial Outer Membranes (C. Danelon & M. Winterhalter).
7. OmpA/OprF: Slow Porins or Channels Produced by Alternative Folding of Outer Membrane Proteins (E. Sugawara & H. Nikaido).
8. Drug Efflux and Protein Export through Channel-tunnels (C. Andersen).
9. Structure-Function Relationships in Sugar-Specific Porins (T. Schirmer).
10. Functional Reconstitution of Specific Porins (R. Benz & F. Orlik).
11. Energy-coupled Outer Membrane Iron Transporters (V. Braun & M. Braun).
12. Structural and Functional Aspects of the Vitamin B12 Receptor BtuB (R. Kadner, et al.).
13. Structure and Function of Mitochondrial (Eukaryotic) Porins (R. Benz).
14. Mitochondrial Porins in Mammals: Insights Into Functional Roles from Mutant Mice and Cells (K. Anflous & W. Craigen).
15. Gene Family Expression and Multitopological Localization of Eukaryotic Porin/Voltage Dependent Anion-selective Channel (VDAC): Intracellular Trafficking and Alternative Splicing (V. De Pinto & A. Messina).
16. Function of the Outer Mitochondrial Membrane Pore (Voltage-dependent Anion Channel) in Intracellular Signalling (M. Vyssokikh & D. Brdiczka).
“This excellent book should be present in all laboratories…the information is extremely up-to-date and is supported by high-quality and highly original graphics.” (International Microbiology, Vol.7, 2004)