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Biochemistry of Signal Transduction and Regulation, 3rd, Completely Revised Edition

ISBN: 978-3-527-60576-7
558 pages
March 2006
Biochemistry of Signal Transduction and Regulation, 3rd, Completely Revised Edition (3527605762) cover image


This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes.
Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis.

"Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie)

"The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry)

"This book is actually two books: Regulation and Signal Transduction." (Drug Research)
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Table of Contents

Regulation of Gene Expression /
Regulation of Enzyme Activity /
Function and Structure of Signaling Pathways /
Signal Transduction by Nuclear Receptors /
G-Protein-Coupled Signal Transmission Pathways /
Intracellular Messenger Substances: "Second Messengers" /
Ser/Thr-Specific Protein Kinases and Protein Phosphatases /
Signal Transmission via Transmembrane Receptors with Tyrosine-Specific Protein Kinase Activity /
Signal Transmission via Ras Proteins /
Intracellular Signal Transduction: Protein Kinase Cascades of MAP Kinase Pathways /
Membrane Receptors with Associated Tyrosine Kinase Activity /
Transmembrane Receptors with Intrinsic Ser/Thr-Kinase Activity and Signal Transduction in the "Two-Component Pathway" /
Regulation of the Cell Cycle /
Malfunction of Signaling Pathways and Tumorigenesis: Oncogenes and Tumor Suppressor Genes /
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Author Information

Gerhard Krauss is Professor of Biochemistry at the University of Bayreuth (Germany). His resarch is centered on the mechanism of interaction of DNA binding proteins and their target DNA. He is specifically interested in transcription factor, DNA methyl transferases and nucleotide excision repair.
The idea for a textbook on Signal Transduction and Gene Regulation originated from a lecture course that he has been teaching at Bayreuth since the middle of the 1990s.
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"In Biochemistry of Signal Transduction and Regulation hat Günther Krauss ein einzigartiges Werk über die biologische Signaltransduktion zusammen gestellt. (...) Die gerade erschienene dritte Auflage dieses Werkes befindet sich auf dem neusten Stand der Forschung. Sie erfüllt mit fundierten Einführungen und penibler Detailtreue die Ansprüche von Spezialisten, wie Wissenschaftlern angrenzender Gebiete, die sich in diese Materie enarbeiten möchten."


"Es sei als ein handlicher, ausgezeichnet lesbarer, kluger Begleiter jedem Studenten, Dozenten und Wissenschaftler für den Weg durch den "Dschungel" der Signaltransduktion wärmstens empfohlen."

Wolf Henning Gebhardt, Student an der École Supérieure de Biotechnologie de Strasbourg

Kommentiertes Vorlesungsverzeichnis der Fachschaft Biologie-, Chemie- und Ernährungswissenschaften der Universität Potsdam, Wintersemester 2004/2005
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