To provide a more cohesive approach to the teaching of pediatric transplantation in various subspecialties, the council of IPTA has initiated the compilation of this book. In organizing the structure of the text, the Editors have recognized that there is a central core of information that is common to all clinical transplantation. Grouped together in the first two sections of the book, this core is intended to provide information about the immune system, rejection and tolerance, immunosuppressives and infection. Organ specific sections are structured in common format designed to cover transplantation, while maintaining the unique needs of the organ specialty.