Biopolymers publishes original research papers and review articles in the general area of macromolecular structure and function, as well as biologically relevant model systems. Manuscripts should report on studies that examine biological macromolecules (naturally occurring and designed), their interactions, reactions, and macromolecular assemblies at structural, chemical, and physical levels. The Journal strives to publish high-impact papers that will significantly enhance our understanding of the chemistry and/or the biology of the systems under investigation. Reports describing techniques that could be applied to the study of biological macromolecules will be considered for publication only if they will have broad utility to the biochemical and biophysical research community.

Topics of particular interest include, but are not limited to:

• Molecular recognition; multi-component complexes and macromolecular assembly, including ordered aggregation
• Molecular design, biomimics, model systems, and bio-nanotechnology
• Biopolymer processing and degradation
• Experimental and theoretical studies of biopolymer folding
• Single molecule studies of biopolymers (e.g., fluorescence, optical tweezers, AFM, etc.)
• Three-dimensional structures of biopolymers determined by X-ray, NMR, EM, other spectroscopic methods, as well as computational prediction
• Bioenergetics of macromolecules and their interactions
• Use of small molecules as either probes or models of structure and function, or as ligands that target biologically relevant receptors
• Preparation and characterization of novel biomaterials

Function may include, for example:

• DNA recombination, replication and repair
• Catalysis
• Molecular motors
• Intracellular signaling and signal transduction
• Chromatin structure and remodeling
• RNA processing
• Transcription
• Translation
• Protein/RNA sorting and trafficking