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Clinical and Translational Science

Vol 10 (6 Issues in 2017)
Edited by: John A. Wagner, MD, PhD
Online ISSN: 1752-8062
Clinical and Translational Science (CTS2) cover image


Clinical and Translational Science (CTS), an official journal of the American Society for Clinical Pharmacology, highlights original research that helps bridge laboratory discovery with the diagnosis and treatment of human disease. Research may appear as Full Articles, Commentaries, Point-Counterpoint, Clinical Trials, or Reviews. CTS also includes invited didactic content that covers the connections between clinical pharmacology and translational medicine. These additional features provide context for research articles and facilitate understanding for a wide array of individuals interested in clinical and translational science. CTS welcomes high quality, scientifically sound original manuscripts focused on clinical pharmacology and translational science, including animal, in vitro, in silico, and clinical studies supporting the breadth of drug discovery, development, regulation and clinical use of drugs. Topics of interest include:

• Hypothesis generating non-clinical and clinical studies, including small clinical trials
• Models of human disease and their therapeutic implications
• Studies that guide Phase 2 dose selection
• Studies that identify or support biomarkers that can be used at any stage of drug development
• Studies that demonstrate effective translation between basic and clinical science
• Regulatory and public health policy implications of translational studies
• PK/PD and quantitative pharmacology as these relate to translational medicine
• Precision medicine and pharmacogenomics
• Translational medicine, including studies focused on Interrogation/evaluation of mechanism-of-action, human physiology, and interruption of disease pathophysiology

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