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Organic Chemistry, Twelfth Edition

Organic Chemistry, Twelfth Edition (EHEP003750) cover image


The 12th edition of Organic Chemistry continues Solomons, Fryhle & Snyder's tradition of excellence in teaching and preparing students for success in the organic classroom and beyond.

A central theme of the authors' approach to organic chemistry is to emphasize the relationship between structure and reactivity. To accomplish this, the content is organized in a way that combines the most useful features of a functional group approach with one largely based on reaction mechanisms. The authors' philosophy is to emphasize mechanisms and their common aspects as often as possible, and at the same time, use the unifying features of functional groups as the basis for most chapters. The structural aspects of the authors' approach show students what organic chemistry is. Mechanistic aspects of their approach show students how it works. And wherever an opportunity arises, the authors' show students what it does in living systems and the physical world around us.

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Table of Contents

1 The Basics Bonding and Molecular Structure 1

2 Families of Carbon Compounds Functional Groups, Intermolecular Forces, and Infrared (IR) Spectroscopy 55

3 Acids and Bases An Introduction to Organic Reactions and Their Mechanisms 104

4 Nomenclature and Conformations of Alkanes and Cycloalkanes 144

5 Stereochemistry Chiral Molecules 193

6 Nucleophilic Reactions Properties and Substitution Reactions of Alkyl Halides 240

7 Alkenes and Alkynes I Properties and Synthesis. Elimination Reactions of Alkyl Halides 282

8 Alkenes and Alkynes II Addition Reactions 337

9 Nuclear Magnetic Resonance and Mass Spectrometry Tools for Structure Determination 391

10 Radical Reactions 448

11 Alcohols and Ethers Synthesis and Reactions 489

12 Alcohols from Carbonyl Compounds Oxidation–Reduction and Organometallic Compounds 534

13 Conjugated Unsaturated Systems 572

14 Aromatic Compounds 617

15 Reactions of Aromatic Compounds 660

16 Aldehydes and Ketones Nucleophilic Addition to the Carbonyl Group 711

17 Carboxylic Acids and Their Derivatives Nucleophilic Addition–Elimination at the Acyl Carbon 761

18 Reactions at the α Carbon of Carbonyl Compounds Enols and Enolates 811

19 Condensation and Conjugate Addition Reactions of Carbonyl Compounds More Chemistry of Enolates 849

20 Amines 890

21 Transition Metal Complexes Promoters of Key Bond-Forming Reactions 938

22 Carbohydrates 965

23 Lipids 1011

24 Amino Acids and Proteins 1045

25 Nucleic Acids and Protein Synthesis 1090

Answers to Selected Problems A-1

Glossary GL-1

Photo Credits C-1

Index I-1

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New To This Edition

WileyPLUS is now equipped with an adaptive learning module called ORION. Based on cognitive science, WileyPLUS with ORION, provides students with a personal, adaptive learning experience so they can build their proficiency on topics and use their study time most effectively. WileyPLUS with ORION helps students learn by learning about them. WileyPLUS with ORION for Organic Chemistry 12e also features new conceptual practice exercises and support for students including

  • Interactive concept map exercises
  • Interactive summary of reactions exercises
  • Interactive mechanism review exercises
  • Video walkthroughs of key mechanisms by the authors

In response to market feedback, the authors have improved the current presentation of the chemistry of benzene rings by moving Ch 21, Phenols and Aryl Halides after Ch15, Reactions of Aromatic Compounds. Other 12e revisions include

  • Synthesizing the Material: new end of chapter problems that requires the student to use synthesis methods across chapters
  •  New Transition Metal Chemistry chapter located after the Ch20, Chemistry of Amines
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The Wiley Advantage

WileyPLUS is a research-based online environment for effective teaching and learning. WileyPLUS has robust interactive study tools and resources–including the complete online textbook–to give your students more value for their money. With WileyPLUS, students will be provided with unique study strategies, tools, and support based on learning styles for success in Organic Chemistry. WileyPLUS hallmarks, such as Reaction Explorer, remain alongside brand-new course updates.

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Instructors Resources
Wiley Instructor Companion Site
Test Bank (Word document format)
Test your students’ comprehension with this digital collection of fill-in-the-blank, multiple-choice, true/false, and free-response questions.
Image PowerPoints
Use this digital repository of images displayed throughout the textbook to enliven your PowerPoint slides and interact with the reading assignments in the classroom.
Clicker Questions
Prepared questions for use in the classroom with your preferred Classroom Response System software.
PowerPoint Presentations
Our PowerPoint™ presentations contain a combination of key concepts allowing you to illustrate important topics with images, figures, and problems from the textbook.
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Students Resources
Wiley Student Companion Site
Student Solutions Manual
Step-by-step instructions explain how to complete a question/problem, providing further assistance to students struggling to come up with the correct answer.
Molecular Visions Model Kits
Practice building molecules in the classroom or at home.
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Purchase Options
Wiley E-Text   
Organic Chemistry with Solutions Manual, Enhanced eText, 12th Edition
ISBN : 978-1-119-24370-0
1944 pages
November 2016, ©2016
$112.00   BUY

Organic Chemistry, 12e Binder Ready Version Study Guide / Student Solutions Manual
ISBN : 978-1-119-07733-6
744 pages
April 2016, ©2016
$137.95   BUY

Organic Chemistry, 12e Study Guide / Student Solutions Manual
ISBN : 978-1-119-07732-9
744 pages
April 2016, ©2016
$196.95   BUY

Organic Chemistry, 12th Edition
ISBN : 978-1-119-07725-1
1200 pages
January 2016, ©2016
$209.95   BUY

Organic Chemistry, 12th Edition
ISBN : 978-1-118-87576-6
1200 pages
November 2017, ©2016
$300.95   BUY

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