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Immunological Reviews

Edited by:
Gary Koretzky


ISI Journal Citation Reports® Ranking: 2008: 6/121 Immunology
Impact Factor: 11.761


While each volume of Immunological Reviews is devoted to a single topic of immunological research, collectively their aim is to provide a broad and continously updated survey of advances in basic immunology and their clinical applications.

TopNews and Announcements

To our Readers,

For 2010, Immunological Reviews will continue its tradition presenting a variety of articles covering a broad topic of immunologic research in each of its six volumes. Experts in each of these areas have graciously agreed to organize volumes with contributions from the leaders in their fields, including those who have been the driving force in establishing the field as well as others in the next generation who are now moving the field forward.

In this first volume for 2010, Dr. Terri Laufer of the University of Pennsylvania has assembled a variety of contributions covering Inflammatory Arthritis. Studies in humans and mouse models have provided a wealth of information about the etiology and pathogenesis of inflammatory arthridites, yet there is still much work to be done to effectively treat patients and prevent these debilitating diseases. Research into rheumatoid arthritis, ankylosing spondylitis, gout, and other related conditions is presented in this issue.

Dr. Ralph Steinman of the Rockefeller University will edit the March volume examining Dendritic Cell Subsets. These cells, first described by Dr. Steinman in 1973, play an essential role in immune system function. The subsets of these cells continue to be defined, and this volume will present the varied functions that they play in the human and animal systems. We look forward to a video podcast interview with Dr. Steinman, which will be available on our website following publication of the volume.

May will bring a volume of reviews covering Cytotoxic Cells. These cells play an essential role in both adaptive and innate immune function and are crucial for the protection of the host against intracellular pathogens. Recent years have seen an explosion in new knowledge melding contributions of cellular immunologists, cell biologists, and biochemists that have informed us of the mechanisms underlying cytotoxic cell function. Dr. Judy Lieberman of Harvard University has commissioned articles covering natural killer cells, cytotoxic T cells, granzymes, and other mediators of cell killing to highlight these new advances.

The fourth volume for 2010 will be edited by Dr. Pippa Marrack of National Jewish Health and the University of Colorado. The reviews in this volume will discuss the mechanisms of Terminating the Immune Response. As pathogenic challenges are met, immune system homeostasis requires that immune cell responses be quelled. Dr. Marrack's volume will provide our readers with cutting edge work describing the myriad of modalities employed to return the immune system to steady state, poised to respond once another challenge is detected.

October's volume will provide an update on B-lymphocyte Biology. While the unique features of how B cells function for immune protection have been an area of interest for decades, recent successes of therapies directed against B cells for many immune-mediated human diseases has intensified our need for a more complete understanding of the biology of this lineage. Dr. Tomo Kurosaki of The Riken Research Center for Allergy and Immunology has commissioned articles that will provide the most up to date research on the many facets of B-cell function including contributions ranging from the most fundamental molecular events important for B-cell development and function to reviews highlighting the role of these cells in disease.

The final volume of the year, Lineage Determination in the Immune System, will be edited by Dr. Ellen Rothenberg of the California Institute of Technology. Much has been learned in recent years about how fate decisions are made during immune cell development and in the periphery as cells of the adaptive immune system adopt their effector functions. This process involves key signaling events, expression and function of critical transcription factors, and epigenetic control mechanisms. Dr. Rothenberg's volume will address each of these control points essential for development of the appropriate repertoire of immune effector cells.

We anticipate that 2010 will be an exciting year for Immunological Reviews and look forward to each of the upcoming volumes. As always, we welcome comments from our readers about articles we publish as well as suggestions for future topics.

Sincerely,

Gary Koretzky
Editor-in-Chief


Forthcoming 2010 Volumes

233 - Inflammatory Arthritis, Guest Editor Dr. Terri Laufer
234 - Dendritic Cell Subsets, Guest Editor Dr. Ralph Steinman
235 - Cytotoxic Cells, Guest Editor, Dr. Judy Lieberman
236 - Terminating the Immune Response, Guest Editor Dr. Pippa Marrack
237 - B Lymphocyte Biology, Guest Editor Dr. Tomo Kurosaki
238 - Lineage Determination in the Immune System, Guest Editor Dr. Ellen Rothenberg

Online Content Now Available Back to Volume 1
All back issues of this journal are available online. For further information on how to access these issues please visit our Librarian Site.

Free Access in the Developing World
Free online access to this journal is available within institutions in the developing world through the AGORA Initiative with the Food and Agriculture Organization of the United Nations (FAO).