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The ISI Impact Factor for Chemical Biology & Drug Design is due in 2008

Chemical Biology & Drug Design

Edited by:
Tomi K. Sawyer


ISI Journal Citation Reports® Ranking: 2008: 150/276 Biochemistry & Molecular Biology
Impact Factor: 2.375


Chemical Biology & Drug Design (CB&DD) is a peer-reviewed scientific journal dedicated to the advancement of innovative science, technology and medicine with a focus on the multidisciplinary fields of chemical biology and drug design. It is the aim of Chemical Biology & Drug Design to capture significant research and drug discovery that highlights new concepts, insight and new findings within the scope of chemical biology and drug design.

Why authors are choosing Chemical Biology & Drug Design:

  • Inexpensive with no submission fees.
  • Online Submission and Review through ScholarOne Manuscripts.
  • International and high-profile Editorial Board.
  • Author Services allows authors to track manuscript from acceptance to publication.
  • Retain Copyright with our Exclusive Licensing Form.
  • Cover Artwork images can be submitted for consideration.
  • Online Open open-access option for authors who wish to pay to make their article freely available online.
  • Early View article-by-article publishing online ahead of print.
  • PDF File of the final article sent to corresponding author.

TopNews and Announcements

CB&DD Early View
Chemical Biology and Drug Design publishes Early View papers - fully reviewed and revised articles published online in advance of publication in a forthcoming printed issue.

CB&DD Online Open
Authors of articles in this journal can now choose to make their articles open access and available free for all readers through the payment of an author fee. Read more.

NIH Public Access Mandate
For those interested in the Wiley-Blackwell policy on the NIH Public Access Mandate, please visit our policy statement.

TopHighlights

Top cited papers
Read articles published in the journal in 2008-2009 that have attracted the most citations for the journal thus far…

Structural characterization and pharmacodynamic effects of an orally active 11 β-hydroxysteroid dehydrogenase type 1 inhibitor
Clarence Hale, Murielle Véniant, Zhulun Wang, Michelle Chen, Jocelyn McCormick, Rod Cupples, Dean Hickman, Xiaoshan Min, Athena Sudom, Haoda Xu, Guy Matsumoto, Christopher Fotsch, David J. St. Jean Jr, Minghan Wang

PDBcal: A comprehensive dataset for receptor-ligand interactions with three-dimensional structures and binding thermodynamics from isothermal titration calorimetry
Liwei Li, Justin J. Dantzer, Jonathan Nowacki, Brian J. O'Callaghan, Samy O. Meroueh

Methods for computer-aided chemical biology. Part 3: Analysis of structure-selectivity relationships through single- or dual-step selectivity searching and bayesian classification
Dagmar Stumpfe, Hanna Geppert, Jürgen Bajorath

3D-quantitative structure-activity relationship studies on benzothiadiazepine hydroxamates as inhibitors of tumor necrosis factor-α converting enzyme
Prashant R. Murumkar, Rajani Giridhar, Mange Ram Yadav

Natural compounds: Leads or ideas? Bioinspired molecules for drug discovery
Terence Beghyn, Rebecca Deprez-Poulain, Nicolas Willand, Benoit Folleas, Benoit Deprez

Novel PPAR-gamma agonists identified from a natural product library: A virtual screening, induced-fit docking and biological assay study
Noeris K. Salam, Tom H-W. Huang, Bhavani P. Kota, Moon S. Kim, Yuhao Li, David E. Hibbs

Synthesis, structural characterization and biological evaluation of novel [1,2,4]triazolo [1,5-b][1,2,4]benzothiadiazine-benzothiazole conjugates as potential anticancer agents
Ahmed Kamal, M. Naseer A. Khan, K. Srinivasa Reddy, Y. V. V. Srikanth, B. Sridhar

Novel druggable hot spots in avian influenza neuraminidase H5N1 revealed by computational solvent mapping of a reduced and representative receptor ensemble
Melissa R. Landon, Rommie E. Amaro, Riccardo Baron, Chi Ho Ngan, David Ozonoff, J. Andrew McCammon, Sandor Vajda

Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use
Evan T. Brower, Usman M. Bacha, Yuko Kawasaki, Ernesto Freire

Atomic property fields: Generalized 3D pharmacophoric potential for automated ligand superposition, pharmacophore elucidation and 3D QSAR
Maxim Totrov

Rhodanine derivatives as selective protease inhibitors against bacterial toxins
Sherida L. Johnson, Li-Hsing Chen, Rebecca Harbach, Mojgan Sabet, Alexei Savinov, Naomi J. H. Cotton, Alex Strongin, Donald Guiney, Maurizio Pellecchia

Chiral N-phosphonyl imine chemistry: Asymmetric aza-Henry reaction
Adiseshu Kattuboina, Parminder Kaur, Teng Ai, Guigen Li

A molecular basis for agonist and antagonist actions at GABAC receptors
Heba Abdel-Halim, Jane R. Hanrahan, David E. Hibbs, Graham A. R. Johnston, Mary Chebib

Pharmacophore modelling and virtual screening for identification of new aurora-a kinase inhibitors
Xiao-Qiang Deng, Hui-Yuan Wang, Ying-Lan Zhao, Ming-Li Xiang, Pei-Du Jiang, Zhi-Xing Cao, Yu-Zhu Zheng, Shi-Dong Luo, Luo-Ting Yu, Yu-Quan Wei, Sheng-Yong Yang

Exploring QSARs for antiviral activity of 4-alkylamino-6-(2-hydroxyethyl)-2-methylthiopyrimidines by support vector machine
Siavash Riahi, Eslam Pourbasheer, Rassoul Dinarvand, Mohammad Reza Ganjali, Parviz Norouzi

Top downloaded papers
Read articles from the journal that have attracted the most full-text accesses in 2009 thus far…

The Structure of Glycosaminoglycans and their Interactions with Proteins
Neha S. Gandhi, Ricardo L. Mancera

AILERON Therapeutics
Tomi K. Sawyer

Identification of Allosteric PIF-Pocket Ligands for PDK1 using NMR-Based Fragment Screening and 1H-15N TROSY Experiments
Brian J. Stockman, Michael Kothe, Darcy Kohls, Laura Weibley, Brendan J. Connolly, Alissa L. Sheils, Qing Cao, Alan C. Cheng, Lily Yang, Ajith V. Kamath, Yuan-Hua Ding, Maura E. Charlton

CREDO: A Protein-Ligand Interaction Database for Drug Discovery
Adrian Schreyer, Tom Blundell

AutoGrow: A Novel Algorithm for Protein Inhibitor Design
Jacob D. Durrant, Rommie E. Amaro, J. Andrew McCammon

Novel Molecular Targets for Antimalarial Drug Development
Nitendra K. Sahu, Sanjeev Sahu, Dharm Veer Kohli

Promises of Biomarkers in Drug Development - A Reality Check
Estelle Marrer, Frank Dieterle

Peptide Nanoparticles as Novel Immunogens: Design and Analysis of a Prototypic Severe Acute Respiratory Syndrome Vaccine
Tais A. P. F. Pimentel, Zhe Yan, Scott A. Jeffers, Kathryn V. Holmes, Robert S. Hodges, Peter Burkhard

Protein-Protein Interactions: A Simple Strategy to Identify Binding Sites and Peptide Antagonists
Annamaria Sandomenico, Simona M. Monti, Marco Sabatella, Antonia De Capua, Laura Tornatore, Nunzianna Doti, Francesca Viparelli, Nina A. Dathan, Carlo Pedone, Menotti Ruvo, Daniela Marasco

A Specific Pharmacophore Model of Aurora B Kinase Inhibitors and Virtual Screening Studies Based on it
Hui-Yuan Wang, Lin-Li Li, Zhi-Xing Cao, Shi-Dong Luo, Yu-Quan Wei, Sheng-Yong Yang

Structural Insights for Design of Potent Spleen Tyrosine Kinase Inhibitors from Crystallographic Analysis of Three Inhibitor Complexes
Armando G. Villaseñor, Rama Kondru, Hoangdung Ho, Sandra Wang, Eva Papp, David Shaw, Jim W. Barnett, Michelle F. Browner, Andreas Kuglstatter

Inhibition of Amyloid Fibril Formation by Polyphenols: Structural Similarity and Aromatic Interactions as a Common Inhibition Mechanism
Yair Porat, Adel Abramowitz, Ehud Gazit

CXCR4, Inhibitors and Mechanisms of Action
Xiangyang Liang

The Race for Chemical and Biological Space: Drug Discovery and Innovative Technologies
Tomi K. Sawyer

A Chemical Genetic Screen for Cell Cycle Inhibitors in Zebrafish Embryos
Ryan D. Murphey, Howard M. Stern, Christian T. Straub, Leonard I. Zon

Rational Design of Multitargeted Tyrosine Kinase Inhibitors: A Novel Approach
Sylvie Barchéchath, Christopher Williams, Khalil Saade, Sylvia Lauwagie, Bertrand Jean-Claude

Histone Deacetylase Inhibition Activity and Molecular Docking of (E)-Resveratrol: Its Therapeutic Potential in Spinal Muscular Atrophy
Didem Dayangaç-Erden, Gamze Bora, Peruze Ayhan, Çetin Kocaefe, Sevim Dalkara, Kemal Yelekçi, Ayhan S. Demir, Hayat Erdem-Yurter

Reversible and Competitive Cinnamoyl Triazole Inhibitors of Tissue Transglutaminase
Christophe Pardin, Isabelle Roy, William D. Lubell, Jeffrey W. Keillor

Novel PPAR-gamma Agonists Identified from a Natural Product Library: A Virtual Screening, Induced-Fit Docking and Biological Assay Study
Noeris K. Salam, Tom H-W. Huang, Bhavani P. Kota, Moon S. Kim, Yuhao Li, David E. Hibbs

Discovery and Binding Studies on a Series of Novel Pin1 Ligands
Bainan Wu, Michele F. Rega, Jun Wei, Hongbin Yuan, Russell Dahl, Ziming Zhang, Maurizio Pellecchia

DNA-binding by Functionalized Gold Nanoparticles: Mechanism and Structural Requirements
Catherine M. Goodman, Nandini S. Chari, Gang Han, Rui Hong, Partha Ghosh, Vincent M. Rotello

Cationic Amphiphilic Polyproline Helices: Side-Chain Variations and Cell-Specific Internalization
Iris Geisler, Jean Chmielewski

The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential
Olayiwola A. Adekoya, Ingebrigt Sylte