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CTS Clinical and Translational Science

Edited by:
Arthur M. Feldman and Scott Waldman


CTS: Clinical and Translational Science is your source for the most current and thought provoking original research across the broad spectrum of clinical specialties and basic science. CTS highlights investigative work bridging the gap between laboratory discovery and practice.

An expert editorial board will help you understand the shape and direction of translational studies and give you insights into the NIH and other routes of translational funding. Articles of varying complexity and depth will give you the choice of how much or how little you wish to read of any one topic. Short communications and news items will provide additional insights into the field.

CTS will discuss the state-of-the-science and strategies that will accelerate the assimilation of genomics and proteomics information into the clinic. As a reader, you will get the information you need, from original research, didactic reviews, expert analysis, to commentary and educational reviews. This peer-reviewed journal provides a clear picture of the rich and complex world that is such a part of translational medicine.

TopNews and Announcements

Clinical and Translational Science is now indexed by ISI! Free content to CTS articles will be accessible through 2010!

Following are the top five most-accessed articles in 2009 published in Clinical and Translational Science:

CTS: A New Discipline to Catalyze the Transfer of Information

Arthur M. Feldman, MD, PhD
Vol. 1, No. 1, May 2008

Urinary Biomarkers for Sensitive and Specific Detection of Acute Kidney Injury in Humans
Vishal S. Vaidya, Sushrut S. Waikar, Michael A. Ferguson, Fitz B. Collings, Kelsey Sunderland, Costas Gioules, Gary Bradwin, Roland Matsouaka, Rebecca A. Betensky, Gary C. Curhan, and Joseph V. Bonventre
Vol. 1, No. 3, December 2008

Use of Salsalate to Target Inflammation in the Treatment of Insulin Resistance and Type 2 Diabetes
Allison B. Goldfine, Robert Silver, Waleed Aldhahi, Dongsheng Cai, Elizabeth Tatro, Jongsoon Lee, and Steven E. Shoelson
Vol. 1, No. 1, May 2008

ErbB2 Induces Notch1 Activity and Function in Breast Cancer Cells
Jaime Lindsay, Ph.D., Xuanmao Jiao, Ph.D., Toshiyuki Sakamaki, Ph.D., Mathew C. Casimiro, Ph.D., Lawrence A. Shirley, M.D., Thai H. Tran, Ph.D., Xiaoming Ju, M.D., Manran Liu, Ph.D., Zhiping Li, M.D., Ph.D., Chenguang Wang, Ph.D., Sanjay Katiyar, Ph.D., Mahadev Rao, Ph.D., Kathleen G. Allen, M.D., Robert I. Glazer, Ph.D., Changhui Ge, Ph.D., Pamela Stanley, Ph.D., Michael P. Lisanti, M.D., Ph.D., Hallgeir Rui, M.D., Ph.D., and Richard G. Pestell, M.D., Ph.D.
Vol. 1, No. 2, September 2008

Sunitinib-Induced Cardiotoxicity Is Mediated by Off-Target Inhibition of AMP-Activated Protein Kinase
Risto Kerkela, Kathleen C. Woulfe, Jean-Bernard Durand, Ronald Vagnozzi, David Kramer, Tammy F. Chu, Cara Beahm, Ming Hui Chen, and Thomas Force
Vol. 2, No. 1, February 2009

STUDY FINDS ANTI-INFLAMMATORY MEDICATION MAY TREAT TYPE 2 DIABETES: Builds on earlier study that showed inexpensive drug may also prevent the disease

BOSTON - May 22, 2008 - Researchers at the Joslin Diabetes Center who reported earlier this year that an inexpensive, non-steroidal anti-inflammatory drug called salsalate might prevent type 2 diabetes are now reporting that the drug may also be beneficial in the treatment of the disease.

The paper, which appears in the May 2008 issue of the journal Clinical and Translational Science (CTS), reports on three proof-of-concept studies that demonstrate that salsalate, which has been used for decades to treat arthritis, may benefit patients with type 2 diabetes by lowering blood sugar and reducing inflammation.

Click here for FREE access to this study

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