Immunological Reviews (IMR) Podcast
Each volume of Immunological Reviews is devoted to a single topic of immunological research and is guest edited by a leading expert in that area. Each volume therefore fills a unique niche by bringing together investigators who have made major contributions to their fields, encouraging them not only to review their area of expertise but also to emphasize their own perspective on the relationship of their work to that of others in the field. In this way, each issue of the Journal provides a broad overview of a defined topic highlighting the newest data, emerging concepts, and areas where there is not yet agreement within the field.
To further explore these unique volumes we are pleased to publish audio podcasts of interviews with the guest editors. Each podcast is free and available for you to download and listen to.
IMR Video Podcast: Dendritic Cell Subsets
In this interview, Dr. Ralph Steinman discusses dendritic cell research, beginning with the studies that led to his discovery of these cells in 1973.
The major finding that dendritic cells, not macrophages, are the primary antigen-presenting cell in the body is discussed, as well as some subsequent surprising findings made by investigators around the world studying this essential immune cell lineage. He offers insights into the direction of future dendritic cell research and closes by giving us an overview of volume 234 of Immunological Reviews, which covers the newest discoveries related to Dendritic Cell Subsets.
Click here to watch. (Flash file, 15 mins 16 secs)
Interview by Justina Stadanlick
Click here to view the full list of review articles in volume 234 of Immunological Reviews
The Guest Editor:
Dr. Ralph Steinman is Henry G. Kunkel Professor and Senior Physician at the Rockefeller University.
IMR Audio Podcast: Mechanisms of Costimulation
In this volume Dr. Arlene Sharpe addresses the key topic of costimulation in the immune system.
For decades it has been known that engagement of immunoreceptors on both B and T lymphocytes is insufficient to elicit a productive immune response. Dr. Arlene Sharpe has assembled many of the individuals who have made the most seminal findings that have informed the immunology community about our current understanding of how costimulation functions to enhance or repress immune system activation.
Click here to listen. (mp3, 6.4mb, 13 mins, 18 secs)
Interview by Wendy Barnaby
Click here to view the full list of review articles being discussed.
The Guest Editor:
Dr Arlene H. Sharpe is currently Professor of Pathology at Harvard Medical School.
IMR Audio Podcast: Kinases and Phosphates of the Immune System
In this volume Dr. Arthur Weiss examines the complex biology of kinases and phosphatases as these enzymes positively and negatively regulate immune cell responses. The contributors to this issue include investigators who have provided the most compelling evidence for the mechanisms by which protein phosphorylation and dephosphorylation exert exquisite control of key pathways in cells of both the adaptive and innate immune systems.
Click here to listen. (mp3, 10.5mb, 14 mins, 58 secs) Interview by Wendy Barnaby
Click here to view the full list of review articles being discussed.
The Guest Editor: Arthur Weiss, M.D., Ph.D. is an internationally recognized immunologist known for seminal contributions to the understanding of the development, regulation and function of T-cells and their roles in human diseases. He also practices clinical rheumatology. Dr. Weiss is an Investigator of the Howard Hughes Medical Institute and holds several positions at the School of Medicine at the University of California including professor of microbiology and immunology and medicine, chief of the division of rheumatology.
He has authored or co-authored more than 200 peer-reviewed scientific publications, and is a member of the editorial boards of Science, Cell, and others.. Dr. Weiss is a member of the National Academy of Sciences, Institute of Medicine and the American Academy of Arts and Sciences and president of the American Association of Immunologists for 2008-2009.
