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Fundamental & Clinical Pharmacology Virtual Issues

Fundamental & Clinical Pharmacology

Published on behalf of the Societe Francaise de Pharmacologie et de Therapeutique and the Federation of the European Pharmacological Societies (EPHAR), and officially affiliated to the ESC Working Group on Cardiovascular Pharmacology and Drug Therapy

TopEditors' choice in Cardiovascular Pharmacology April 2008

The pharmacologic elegance of inhibiting cholesterol absorption and synthesis while providing a homeostatic balance
A. L. Catapano

Sympathetic control of short-term heart rate variability and its pharmacological modulation
Jean-Luc Elghozi, Claude Julien

Melatonin counteracts the loss of agonist-evoked contraction of aortic rings induced by incubation
Isabelle Lartaud, Sebastien Faure, Aurore Tabellion, Angela Resende, Sophie Nadaud, Denyse Bagrel, Christine Capdeville-Atkinson, Jeffrey Atkinson

Clinical Pharmacology in the Geriatric Patient
Sarah Hilmer, Andrew McLachlan, David Le Couteur

Rationale, Design and Methods of the OSCAR Study: Observational Study on Cognitive Function and Systolic Blood Pressure Reduction in Hypertensive Patients.
Atul Pathak, Olivier Hanon, Laurence Negre-Pages, Franck Sevenier

Blood pressure lowering efficacy of olmesartan relative to other angiotensin II receptor antagonists. An overview of randomized controlled studies.
Faiez Zannad, Renaud Fay

Understanding the estrogen action in experimental and clinical atherosclerosis.
J.F. Arnal, V. Douin-Echinard, L. Brouchet, F. Tremollieres, H. Laurell, F. Lenfant, A.P. Gadeau, J.C. Guery, P. Gourdy

Clinical methods for the evaluaation of endothelial function - a focus on resistance arteries
Adeline Paris, Catherine Cornu, Pascal Antiquier, Patrick Maison, Anca Radauceanu, Christian Brandt, Muriel Salvat-Melis, Marc Hommel, Jean-Luc Cracowski

Early pharmacological preconditioning by erythropoietin medicated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart
M Joyeux-Faure, A Ramond, P.C. Béguin, E Belaïdi, D Godin-Ribuot, C Ribuot

Apparent effect on blood pressure is only partly responsible for the risk reduction due to antihypertensive treatments
Jean-Pierre Boissel, Francois Gueyffier, Florent Boutitie, Stuart Pocock, Robert Fagard

Erythropoietin and myocardial protection: whats new?
M Joyeux-Faure, D Godin-Ribuot, C Ribuot

Vascular and renal actions of Brain Natriuretic Peptide in man: physiology and pharmacology
Peter De Leeuw, Alphons Houben, Kim van der Zander

Effects of melatonin and caffeic acid phenethyl ester on testicular injury induced by myocardial ischenia/reperfusion in rats
M Esrefoglu, Mehmet Gul, Hakan Parlakpinar, Ahmet Acet

Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update
Michael Schachter

G protein- coupled receptors: a count of 1001 conformations
I Van Liefde, Georges Vauquelin