PART I - Molecules and Life

Chapter 1     ===     Biochemistry: Setting the Stage

1.1

The Roots of Modern Biochemistry

Hot Careers Cutting Edge Article
Visionaries of Science Cutting Edge Article

1.4

Organelles, Cells, and Organisms

Cell Structure Interactive Animation

Chapter 2     ===     The Flow of Biological Information: Cell Communication

2.1

Storage of Biological Information in DNA

Visionaries of Science Cutting Edge Article
DNA Structure Tutorial
Central Dogma of Biochemistry Interactive Animation

2.2

Transfer of Biological Information to RNA

DNA Structure Tutorial
Central Dogma of Biochemistry Interactive Animation

2.3

Protein Synthesis

Protein Synthesis Interactive Animation

2.5

Information Flow through Cell Membranes

Signal Transduction Interactive Animation

2.6

Diseases of Cell Communication and Drug Design

Anthrax Cutting Edge Article

Chapter 3     ===     Biomolecules in Water

3.1

Water, the Biological Solvent

Molecular Recognition Cutting Edge Article
Water, pH, and Non-covalent Bonding Concept Review

3.2

Hydrogen Bonding and Solubility

Water, pH, and Non-covalent Bonding Concept Review

3.3

Cellular Reactions of Water

Logarithms Concept Review
Water, pH, and Non-covalent Bonding Concept Review

Chapter 4     ===     Amino Acids, Peptides, and Proteins

4.1

The Amino Acids in Proteins

Amino Acids Game Interactive Animation

4.3

Protein Function

Antibodies Structure Tutorial

Part II Dynamic Function of Biomolecules

Chapter 5     ===     Protein Architecture and Biological Function

5.2

Elements of Secondary Structure

Intro to Chime with Secondary Structure Structure Tutorial

5.3

Protein Tertiary Structure

Protein Folding Interactive Animation

5.5

Protein Structure and Biological Function

Prions Cutting Edge Article
Antibodies Structure Tutorial
Kinesin Structure Tutorial
Myoglobin and Hemoglobin Structure Tutorial

Chapter 6     ===     Enzymes I: Reactions, Kinetics, and Inhibition

6.1

Enzymes as Biological Catalysts

Visionaries of Science Cutting Edge Article
Catalysis Interactive Animation
Elementary Kinetics Concept Review

6.2

The Kinetic Properties of Enzymes

Elementary Kinetics Concept Review

6.3

Substrate Binding and Enzyme Action

Enzyme Specificity Interactive Animation

6.4

Enzyme Inhibition

AIDS Therapies Cutting Edge Article
Enzyme Inhibition Interactive Animation

Chapter 7     ===     Enzymes II: Coenzymes, Regulation, Catalytic Antibodies, and Ribozymes

7.4

Abzymes

Catalytic Antibodies Cutting Edge Article
Antibodies Structure Tutorial

7.5

Catalytic RNA

Ribozymes Cutting Edge Article

Chapter 8     ===     Carbohydrates: Structure and Biological Function

8.3

Reactions of Monsaccharides

Lactose Intolerance Cutting Edge Article

8.5

Glycoproteins

Molecular Recognition Cutting Edge Article

Chapter 9     ===     Lipids, Biological Membranes, and Cellular Transport

9.2

Triacylglycerols

Fat Blockers Cutting Edge Article

9.4

Steroids and Other Lipids

Cholesterol Interactive Animation

9.6

Membrane Transport

Cellular Transport Interactive Animation

Part III - Storage and Transfer of Biological Information

Chapter 10     ===     DNA and RNA: Structure and Function

10.1

RNA and DNA Chemical Structures

AIDS Therapies Cutting Edge Article
Central Dogma of Biochemistry Interactive Animation
Nucleotides Game Interactive Animation

10.2

DNA Structural Elements

Visionaries of Science Cutting Edge Article
DNA Structure Tutorial

10.3

RNA Structural Elements

tRNA Structure Tutorial

10.4

Cleavage of DNA and RNA by Nucleases

Restriction Digestion and Electrophoresis Interactive Animation

10.5

Nucleic Acid-Protein Complexes

AIDS Therapies Cutting Edge Article

Chapter 11     ===     DNA Replication and Transcription: Biosynthesis of DNA and RNA

11.1

Replication of DNA

DNA Replication Interactive Animation

11.2

Action of DNA Polymerases

Telomeres Cutting Edge Article

11.5

Post-transcriptional Modification of RNA

Ribozymes Cutting Edge Article

Chapter 12     ===     Translation of RNA: The Genetic Code and Protein Metabolism

12.1

The Process of Protein Synthesis

Central Dogma of Biochemistry Interactive Animation
tRNA Structure Tutorial

12.2

The Three Stages of Protein Synthesis

Molecular Recognition Cutting Edge Article
Ribozymes Cutting Edge Article
Protein Synthesis Interactive Animation

12.4

Regulation of Protein Synthesis

Molecular Recognition Cutting Edge Article
Protein-DNA Interactions Structure Tutorial

Chapter 13     ===      Recombinant DNA and Other Topics in Biotechnology

13.1

Recombinant DNA Technology

Cloning Interactive Animation

13.2

Preparing Recombinant DNA

Shotgun Sequencing

13.3

DNA Amplification by PCR

DNA Fingerprinting Cutting Edge Article
Polymerase Chain Reaction Interactive Animation

13.4

Applications of Recombinant DNA Technology

Hot Careers Cutting Edge Article

Part IV - Metabolism and Energy

Chapter 14     ===     Basic Concepts of Cellular Metabolism and Bioenergetics

14.1

Intermediary Metabolism

Introduction to Metabolism Interactive Animation

14.2

The Chemistry of Metabolism

Introduction to Metabolism Interactive Animation
Redox Reactions Concept Review

14.3

Concepts of Bioenergetics

Logarithms Concept Review
Thermodynamics Concept Review

Chapter 15     ===     Metabolism of Carbohydrates

15.1

The Energy Metabolism of Glucose

Hexokinase Structure Tutorial
Phosphofructokinase Structure Tutorial
Glycolysis Interactive Animation

15.3

Pyruvate Metabolism

Alcohol Abuse Cutting Edge Article

15.4

Biosynthesis of Carbohydrates

Methanol as Fuel Cutting Edge Article
Gluconeogenesis Interactive Animation

15.5

Regulation of Glycolysis

Hexokinase Structure Tutorial
Phosphofructokinase Structure Tutorial

Chapter 16     ===     Production of NADH, and NADPH: The Citric Acid Cycle, Glyoxylate Cycle and the Phosphogluconate Pathway

16.1

The Pyruvate Dehydrogenase Complex

Pyruvate Dehydrogenase Complex Interactive Animation

16.2

The Citric Acid Cycle

Citric Acid Cycle Interactive Animation

Chapter 17     ===     ATP Formation by Electron-Transport Chains

17.1

Mitochondrial Electron Transport

Redox Reactions Concept Review

17.3

Oxidative Phosphorylation

Oxidative Phosphorylation Interactive Animation

17.5

Photosynthetic Electron Transport

Photosynthesis Interactive Animation

17.6

Synthesis of Carbohydrates by the Calvin Cycle

Methanol as Fuel Cutting Edge Article

Chapter 18     ===     Metabolism of Fatty Acids and Lipids

18.1

Metabolism of Dietary Triacylglycerols

Fat Blockers Cutting Edge Article
Fatty Acid Metabolism Interactive Animation

18.2

Catabolism of Fatty Acids

Fatty Acid Metabolism Interactive Animation

18.4

Cholesterol

Cholesterol Interactive Animation
Endocrine-Disruptors Cutting Edge Article

Chapter 19     ===     Metabolism of Amino Acids and Other Nitrogenous Compounds

19.2

Biosynthesis of Amino Acids

Homocysteine Cutting Edge Article

19.5

Amino Acids as Precursors of Other Biomolecules

Nitric Oxide and Viagra Cutting Edge Article

Chapter 20     ===     Integration, Coordination, and Specialization in Metabolism

20.2

Metabolic Specialization and Integration

Cori Cycle Interactive Animation
Metabolic Process Location Interactive Animation

20.2

Window on Biochemistry

Fat Blockers Cutting Edge Article

Copyright 2002, John Wiley & Sons Publishers, Inc.