Principles of Genetics, Chapters 1 - 14
1 Science of Genetics
- History of Genetics Timeline
- Part of the Access Excellence Project for K-12 science instruction.
- Glossary
- A comprehensive genetics glossary developed by the Department of Energy.
- talk.origins/Evolution Echo Jargon File
- Terms and phrases appearing in the talk.origins newsgroup and the Evolution Echo of Fidonet; with links to Frequently Asked Questions (FAQ)
- Diving into the Gene Pool
- A site that explores some ethical issues raised by the Human Genome Project. Visitors to the site can also submit comments and opinions for posting via the ETHEX mailing list.
2 Reproduction as Basis of Heredity
- Introduction to Virtual FlyLab
- A Web-based fly genetics lab.
- A case study of genetics research applied to a medical problem.
- UCSF WWW Page-The ABCs of DNA
- An introduction to DNA, inheritance and molecular biotechnology.
- Inheritance of Hemophilia
- An illustration of how hemophilia in humans is inherited.
- Recessive and Dominant Inheritance
- A brief illustrated description of one mode of inheritance.
- Sex-Linked Inheritance
- A brief illustrated description of how genes on sex chromosomes are inherited.
- Welcome to GenCalc
- In this "genetic calculator" you get to choose the traits that
the parents will pass on to the child and this program will tell you the percentage chance that the child will receive the trait that you have chosen.
-
Mendel and Heredity
- A good overview of Mendelian genetics including colour display plates to assist in the explanation
3 Mendelism: the Basic Principles of Inheritance
- About Johann Gregor Mendel
- A short biography of Gregor Mendel from the Czech Republic (in English).
- Cell Division Tutorials
- A tutorial, with problems and answers, on the genetic consequences of cell division.
- Genetics Lectures
- A Genetics survey course home page with other Genetics links
- Department of Genetics Courses
- Links to course notes for Genetics
at the University of Washington
- MendelWeb Table of Contents
- A comprehensive source of Genetics links and information, including Mendel's 1865 paper.
- Classic Papers in Genetics
- Descriptions of some classic Genetics papers, with links to pdf versions.
- notes100996.html
- Basic Genetics principles, from lecture notes at the University of Washington.
- notes101596.html
- An overview of agricultural genetics
- Introduction to Virtual FlyLab
- Background information and protocols for Genetic experiments using yeast.
- Tribolium Home Page
- Genetic information about the red flour beetle, Tribolium castaneum
- GenScope
- A novel computer program for studying genetics from the molecular to the population level.
- Fundamentals of Inheritance
- The principles of Mendelian inheritance.
4 Extensions of Mendelism
- notes101696.html
- Lecture notes on epistasis.
- notes102196.html
- Examples of polygenic traits.
- Gene Interactions and Epistasis
- A description of possible interactions between genes and mechanisms of differential gene expression.
- Genetic Analysis of
Vulval Development in C. elegans
- An example of epistatic interactions during development.
- The Pigment Parade
- An example of epistasis: white pelt colora
tion in cats.
5 The Chromosomal Basis of Mendelism
- Tribolium Home Page
- Genetic information about the red flour beetle, Tribolium castaneum
- National Human Genome Research Institute
- A central site for information about the Human Genome Project.
- Berkeley Drosophila Genome Project
- Information about a consortium that is determining the complete DNA sequence of the euchromatic genome of the fruitfly, Drosophila melanogaster.
- The E. coli Genome Center
- The entire genome of the bacterium E. coli.
- Online Mendelian Inheritance in Man
- A catalog of human genes and genetic disorders.
- Sex Linkage
- Practice problems involving sex linkage.
6 Variation in Chromosome Number and Structure
- New Methods for Karyotyping
- Karyotyping of human chromosomes using several fluorescent dyes that reveal translocations and other ano
molies.
- Primate Cytogenetics Network
- A clearinghouse for information on primate karyotypes, ideograms and digital images, including human samples.
- Karyotyping Activity
- This exercise is a simulation of human karyotyping using digital images of chromosomes from actual human genetic studies.
- Karyotype Samples
- A link to a Shockwave for Director-based site that allows you to karyotype normal and abnormal karyotypes.
- Human Genetics Problem Set
- Several problems related to PCR, pedigrees, aneuploidy and sex linkage.
- Drosophila Aberrations
- A database of chromosomal abnormalities in Drosophila
- Online Mendelian Inheritance in Man
- A catalog of human genes and genetic disorders.
- Featured Genes
- A selected list of human disease genes, with information on chromosome location and descriptions of each disorder.
- notes100296.html
- Aneuploidy and chromosomal rearrangements in the study of meiosis.
7 Linkage , Crossing Over and Mapping in Eukaryotes
- FlyBase Genes
- A database of the Drosophila genome.
- The Dog Genome Project
- The techniques used and data collected on dog genes responsible for behavior and diseases.
- The Maize Genome Database Project
- A database of known corn genes.
- Roslin Institute Online
- Information on genetic research on farm animals.
- Virtual Genome Center
- A list of links useful for evaluating sequence data.
- Primer on Molecular Genetics (Department of Energy)
- Chromosome maps derived from the Human Genome Project.
- Search OMIM -- Online Mendelian Inheritance in Man
- A searchable database of human genes, both normal and disease-related.
- Problem Index
- A list of genetics problems, with answers, grouped by subject.
- Introduction to Virtual FlyLab
Background information and protocols for Genetic experiments using yeast.
- Tribolium Home Page
- Genetic information about the red flour beetle, Tribolium castaneum
- Saccharomyces Genome Database
- Genomic and biological information on baker's yeast, Saccharomyces cerevisiae
- GenScope
- A novel computer program for studying genetics from the molecular to the population level.
- VL: Genetics
- Gene mapping strategies and movement of genes.
- Featured Genes
- Different types of DNA polymorphisms.
8 Advanced Linkage Analysis
- FlyBase Genes
- A database of the Drosophila genome.
- The Dog Genome Project
- he techniques u
sed and data collected on dog genes responsible for behavior and diseases.
- The Maize Genome Database Project
- A database of known corn genes.
- Roslin Institute Online
- Information on genetic research on farm animals.
- Virtual Genome Center
- A list of links useful for evaluating sequence data.
- Problem Index
- A list of genetics problems, with answers, grouped by subject.
- BCM Search Launcher
- Links to molecular biology-related search engines and analysis services.
- NCBI BLAST Search
- A sequence analysis tool for comparing nucleotide or peptide sequences.
9 DNA and the Structure of Chromosomes
- James Dewey Watson
- A biography of one of the co-discoverers of the genetic code.
- Virtual Genome Center
- A list of links useful for evaluating sequence data.
- Primer on Molecular Genetics (Department of Energy)
- What chromosomes look like, with examples.
- Saccharomyces Genome Database
- A database containing the genome of the yeast Saccharamyces
- The Molecular Basis of Genetics
- Replication and estimates of genome size.
10 DNA and Chromosome Replication
- Problem Index
- DNA structure and replication.
- mg501n12.html
- DNA replication, repair, mutation and recombination.
- lecture960126.html
- Illustrated lecture notes on DNA structure and replication.
- Topoisomerase Action
- An enzyme involved in DNA replication.
- DNA Replication
- DNA replication. Part of MIT's Biology Hypertextbook.
11 Transcription and RNA processing
- Problem Index
- A list of genetics problems, with answers, grouped by subject.
- UCSF WWW Page-The ABCs of DNA
- An overview of the structure of DNA, genes, and chromosomes.
- The Human Transcript Map
- A comparison between prokaryotic and eukaryotic transcription.
- Transcription of RNA from DNA
How genetic information gets from the nucleus to the rest of the cell.
12 Translation and the Genetic Code
- Problem Index
- The Yeast Protein Database, with links to other yeast and sequence analysis sites.
- GenScope
- A novel computer program for studying genetics from the molecular to the population level.
- UCSF WWW Page-The ABCs of DNA
- Transcription and translation.
- Codon Usage D
atabase
- The frequency of codon use in each organism from the GenBank sequence database is searchable through this World Wide Web site.
- Translation of RNA to
Protein
- How messenger RNAs direct protein synthesis.
13 Mutation, Recombination and DNA Repair
- Barbara McClintock
- A biography of the discoverer of transposable elements.
- Cold Spring Harbor Laboratory Online (CLIO)
- An important center for research on the genetics of cancer.
- The Maize Genome Database Project
- A database of known corn genes.
- Primer on Molecular Genetics (Department of Energy)
- An introduction to DNA, transcription and translation.
- Problem Index
- A list of genetics problems, with answers, grouped by subject.
- Welcome to GENE:Yeast Experiments
- Background information and protocols for Genetic experiments using yeast.
- Tribolium Home Page
- Errors in replication.
14 Definitions of the Gene
- Primer on Molecular Genetics (Department of Energy)
- Background information and protocols for Genetic experiments using yeast.
- Glossary
- A comprehensive genetics glossary developed by the Department of Energy.
- James D. Watson
- A biography of one of the discoverers of the structure of DNA.