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The help sections below cover problems you might encounter related to operating
system and Web bowser compatibility. Plug-in requirements and installation are
also discussed, but these considerations are not an issue if you are viewing the
content from the browser running off the Essential Biochemistry CD. Also
included below are helpful hints for using some of the technologies found on the
Web site.
Use the menu at right to navigate to the help section that would pertain to
the question you have or adresses the problem you might be experiencing.
GENERAL HELP 
System requirements
PC: Windows 95 or greater, 233 MHz processor and 64 MB RAM or greater recommended.
Macintosh: Mac OS 8.6 or greater, 333 MHz processor and 64 MB RAM or greater
recommended.
Software requirements
The biomolecular structure exercises require both Netscape
Navigator 4 (or Communicator 4) and Chemscape
Chime 2. Later versions of Navigator will not work. The animated exercises
require version 6 (or higher)
of the Flash plugin. For the Instructor Resources, Microsoft PowerPoint is
necessary to access the included presentation files. Microsoft Word is required
to access the included handouts. Adobe Acrobat
Reader version 6 or greater is needed to view the multimedia handbooks.
Navigation problems
If at any time your browser becomes "jammed up," such that the navigational
tabs do not appear to be functioning, simply press the "reload" button
on your browser to restore the proper functioning of the navigational elements
of the Web site.
FLASH HELP 
Essential Biochemistry contains many animations that require
version 6 (or higher) of the Flash plugin. This is not an issue if you are
viewing the content from the browser running off the Essential Biochemistry
CD.
If you are getting errors...
If you are having problems with the animations, you are likely not viewing
them using the browser pre-installed on the Essential Biochemistry CD,
and are using your own browser to view the CD or Web site. This leads to plug-in
compatibility issues, which is why it is recommended that you use the self-contained
browser on the CD. If you have an Essential Biochemistry CD, quit your
current browser and re-launch the StartHere application.
Animation interface
Notes on the Essential Biochemistry animation interface:
- The stop button pauses the animation
- The play button is used to continue playing the animation after you
have reached programmed pauses in the animation
- The next and previous buttons take you to another section
of the animation. These sections are based around major concepts within the
animation, and may contain more than one screen
- The drop-down menu allows you to navigate to any section within the
animation
Notes on the functionality of the animations:
- When you are asked a review question, you must attempt to answer it before
proceeding with the play button.
- If you mute the animation, a text window will pop-up so that you can read
the information present in the audio voiceover.
CHIME HELP 
Essential Biochemistry contains many structure tutorials that require
both Netscape Navigator
4 (or Communicator) and Chemscape
Chime 2. This is not an issue if you are viewing the content from the browser
running off the CD.
If you are getting errors...
If you are having problems with the visualization of molecules in the structure
tutorials, you are likely not viewing them using the browser pre-installed on
the Essential Biochemistry CD, and are using your own browser to view the
CD or Web site. This leads to plug-in compatibility issues, which is why it is
recommended that you use the self-contained browser on the CD. If you have an
Essential Biochemistry CD, quit your current browser and re-launch the
StartHere application.
Chem3D Conflicts (Windows only)
Older versions (pre-version 6) of the Chem3D plug-in (installed with the CambridgeSoft
ChemOffice suite of chemistry applications) edit the registry of Windows computers,
effectively commandeering the molecular structure coordinate file types away from
Chime. This results in a strange (and unintended) display of the 3D molecules
or a blank plug-in display typical of an uninstalled Chime plug-in. This remains
a problem even when running the self-contained browser on the CD or any browser
which has Chime properly installed.
This media software will not influence your registry, even to exorcise the
Chem3D registry items in order for Chime to be functional. If you are experiencing
this problem, here are two possible solutions, the second of which will work in
all cases:
- Download and install the very latest version of Chemscape
Chime on your computer (even if you are using the self-contained browser on
the CD). CambridgeSoft has reported that Chime can take back the file types it
needs to function. If you still want to run Chem3D alongside Chime, you can then
install version 6 or greater of the Chem3D plug-in, which will not interfere with
Chime.
- Edit your registry (use extreme caution when doing so, for mistakes can lead
to an inoperable computer):
- Launch Regedit, HKey_Classes_Root\MIME\Content Type\
- Look for the MIME Types associated with structural files (such as ".pdb"
and ".xyz") and delete any associated with Chem3D Plugin, that you don't
want associated with the Chem3D Plugin.
- Open the File Types (the location of this varies depending on the version
of Windows) and reassign any file types that are set to the Chem3D to CHIME.
- Restart your computer.
Please refer to CambridgeSoft for dealing with this problem:
How
do I manipulate the molecules myself?
Windows
- To freely rotate the molecule, just click anywhere
on the molecule and drag it in the direction you want
to rotate using the left mouse button.
- To zoom in and out, hold down the shift key
while clicking and dragging.
- To translate (change the location of) the molecule
on your screen, hold down the control key while
clicking and dragging with the right mouse button.
- To bring up a menu with a powerful list of commands
for displaying the molecule (the Chime menu), simply
click on the molecule with the right mouse button.
Macintosh
- To freely rotate the molecule, just click anywhere on the molecule
and drag it in the direction you want to rotate.
- To zoom in and out, hold down the shift key while clicking
and dragging.
- To translate (change the location of) the molecule on your screen
the molecule, hold down the control and option keys
while clicking and dragging.
- To bring up a menu with a powerful list of commands for displaying
the molecule (the Chime menu), simply click and hold down the
mouse button on the molecule, without dragging.
How
do I use the Chime menu?
The Chime menu is a pop-up hierarchical menu that can be brought
up on top of any structure displayed by Chime. To access the menu:
Windows
Click on the area of your screen occupied by the embedded Chime
object while holding down the control key.
Macintosh
Click on the area of your screen occupied by the embedded Chime object and
hold the button down for a second without dragging.
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