To request review copies
translationrights@wiley.com
Back to contents
85
Biochemistry
Fundamentals of Intracellular Calcium
Anthony K. Campbell
ISBN: 978-1-118-94187-4 | Oct 2017 | 464PP
The definitive text on the key component for cell functions — intracellular
calcium
This comprehensive book reveals the evidence for intracellular calcium as a
universal switch in all animal, plant, fungal and microbial cells. It shows how the
components required for calcium signaling are named and classified; covers the
technology that has been developed to study intracellular calcium; describes how
calcium is regulated inside cells and how it works to trigger an event; explains the
role of intracellular calcium in disease, cell injury, and cell death; reveals how
many drugs work through the calcium signaling system; and demonstrates how
intracellular calcium is involved in the action of many natural toxins. The book
also illustrates how the intracellular calcium signaling system has evolved over
millions of years, showing why it was crucial to the origin of life. Additionally, the
book promotes the importance of the molecular variation upon which the
intracellular calcium signalling system depends.
Featuring more than 100 figures (including detailed chemical structures as well as
pictures of key pioneers in the field), a bibliography of some 1000 references, and
a detailed subject index, this definitive work provides a unique source of
scholarship for teachers and researchers in the biomedical sciences and beyond.
•• Emphasizes two key scientific principles — the first to show how intracellular
Ca2+ acts as a switch, to activate a wide range of cellular events, and the second
demonstrating how an analogue mechanism can be superimposed on such a
process
•• Written by an internationally recognized expert in the field
•• Filled with images and references to facilitate learning
About the Author
Anthony K. Campbell, PhD, FLS, FLSW, is Professor in the School of Pharmacy
and Pharmaceutical Sciences, Cardiff University.