Genetics Genomics Proteomics Bioinformatics   GENETICS Genetic Variation & Evolution id number >> Section Editor: David B. Goldstein, Duke University Medical Center, North Carolina, USA Population genomics: patterns of genetic variation within populations - Greg Gibson Modeling human genetic history - Lounès Chikhi, Mark A. Beaumont Homeobox gene repertoires: implications for the evolution of diversity - Claudia Kappen The genetic structure of human pathogens - Daniel J. Wilson, Daniel Falush The role of gene regulation in evolution - Matthew V. Rockman Studies of human genetic history using the Y chromosome - Mark A. Jobling Modeling protein evolution - David D. Pollock, Richard A. Goldstein Genetic signatures of natural selection - Molly Przeworski, Carlos D. Bustamante Studies of human genetic history using mtDNA variation - Antonio Torroni, Chiara Rengo Measuring variation in natural populations: a primer - Henry Harpending Cytogenetics id number >> Section Editor: Terry Hassold, Washington State University, Washington, USA Human cytogenetics and human chromosome abnormalities - Terry Hassold Visualising human chromosomes - Stuart Schwartz Human X chromosome inactivation - Samuel C. Chang, Carolyn J. Brown Acquired chromosome abnormalities: the cytogenetics of cancer - Susanne M. Gollin Cytogenetic aspects of meiosis - Hazel Baker, Maira Tankimanova, Maj Hultén Microdeletions - John A. Crolla Nondisjunction - Neil E. Lamb Cytogenetics of infertility - Maria Oliver-Bonet, Renée H. Martin Preimplantation genetic diagnosis for chromosome abnormalities - Santiago Munné Mosaicism - Wendy P. Robinson Uniparental disomy - Aaron P. Theisen, Lisa G. Shaffer Cytogenetic analysis of lymphomas - Douglas E. Horsman Comparative genomic hybridization - Brynn Levy FISH - P. Nagesh Rao, Mark J. Pettenati Human sperm--FISH for identifying potential paternal risk factors for chromosomally abnormal reproductive outcomes - Andrew J. Wyrobek, Thomas E. Schmid, Francesco Marchetti Epigenetics id number >> Section Editor: Robert Nicholls, University of Pennsylvania, Philadelphia, USA and Benjamin Tycko, Columbia University, New York, USA Imprinting and epigenetic inheritance in human disease - Constantin Polychronakos The histone code and epigenetic inheritance - Andrew R. Hoffman, Thanh H. Vu Imprinting at the GNAS locus and endocrine disease - Lee S. Weinstein, Min Chen, Akio Sakamoto, Jie Liu Imprinting and epigenetics in mouse models and embryogenesis: understanding the requirement for both parental genomes - Mellissa R. W. Mann Beckwith-Wiedemann syndrome - Benjamin Tycko, Marcel Mannens Imprinting in Prader-Willi and Angelman syndromes - Bernhard Horsthemke, Karin Buiting DNA methylation in epigenetics, development, and imprinting - Hiroyuki Sasaki Mechanisms of epigenetic loss of chromosomes in insects - Clara Goday, Maria-Fernanda Ruiz Imprinted QTL in farm animals: A fortuity or a common phenomenon? - Martien A.M. Wageningen Evolution of genomic imprinting in mammals - Hamish G. Spencer Imprinting and behavior - James P. Curley, Eric B. Keverne Initiation of X-chromosome inactivation (or X-chromosome inactivation: counting, choosing, inactivating) - Lygia V. Pereira, Raquel Stabellini Epigenetics and imprint resetting in cloned animals - K.John McLaughlin, Satoshi Kurosaka, Sigrid Eckardt Epigenetic reprogramming in germ cells and preimplantation embryos - Abraham L. Kierszenbaum Rapidly evolving imprinted loci - Joomyeong Kim, Lisa Stubbs Epigenetic inheritance and RNAi at the centromere and heterochromatin - Kristin S. Caruana Scott, Beth A. Sullivan Variable expressivity and epigenetics - Marnie E. Blewitt, Emma Whitelaw Spreading of X chromosome inactivation - Jason O. Brant, Thomas P. Yang Techniques in genomic imprinting research - Todd A. Gray Bioinformatics and identification of imprinted genes in mammals - John M. Greally, Melissa J. Fazzari UPD in human and mouse and role in identification of imprinted loci - Aaron P. Theisen, Lisa G. Shaffer Gene Mapping id number >> Section Editor: Nancy J. Cox, University of Chicago, Illinois, USA Introduction to gene mapping: Linkage at a crossroads - Nancy J. Cox Parametric vs. non-parametric and two-point vs. multipoint: controversies in gene mapping - Joan E. Bailey-Wilson Gene mapping and the transition from STRPs to SNPs - Ellen M. Wijsman Gene mapping, imprinting and epigenetics - Konstantin Strauch Algorithmic improvements in gene mapping - Gonçalo R. Abecasis, Yu Zhao Sex-specific maps and consequences for linkage mapping - Solveig K. Sieberts, Daniel F. Gudbjartsson Information content in gene mapping - Dan L. Nicolae Choices in gene mapping: populations and family structures - Toni I. Pollin, Jeffrey R. O'Connell Polymorphic inversions, deletions, and duplications in gene mapping - Susan L. Christian Computation of LOD scores - Anthony L. Hinrichs, Brian K. Suarez Complex Traits and Diseases id number >> Section Editor: Leena Peltonen, Biomedicum Helsinki, Finland Genetics of complex diseases: Lessons from type 2 diabetes - Leif Groop, Peter Amgen The common disease common variant concept - Deborah S Cunninghame Graham, Timothy J. Vyse Population selection in complex disease gene mapping - Teppo Varilo, Leena Peltonen Concept of complex trait genetics - Kenneth M. Weiss, Anne V. Buchanan Allergy and asthma - Miriam F. Moffatt, William O.C. Cookson Complexity of cancer as a genetic disease - Tea Vallenius, Tomi P. Mäkelä Genetics of cognitive disorders - Brett S. Abrahams, Daniel H. Geschwind Hypertension genetics: under pressure - Fadi J. Charchar, Maciej Tomaszewski, Anna F. Dominiczak Inflammation and inflammatory bowel disease - Christopher G. Mathew The mitochondrial genome - Douglas C. Wallace Genetic Medicine and Clinical Genetics id number >> Section Editor: Bruce Korf, University of Alabama at Birmingham, USA Approach to common chronic disorders of adulthood - Maren T. Scheuner Approach to rare monogenic and chromosomal disorders - Marc S. Williams Current approaches to prenatal screening and diagnosis - Paula C. Cosper Advances in newborn screening for biochemical genetic disorders - Inderneel Sahai, Harvey L. Levy Advances in cytogenetic diagnosis - Daynna J. Wolff Current approaches to molecular diagnosis - O. Thomas Mueller The clinical and economic implications of pharmacogenomics - David L. Veenstra Molecular dysmorphology - Leslie G. Biesecker Ethical and legal issues in medical genetics - Mary Kay Pelias Changing paradigms of genetic counseling - Katherine A. Schneider, Vickie Venne Mechanisms of inheritance - Arthur S. Aylsworth Family history, pedigree analysis, risk assessment - Robin L. Bennett Genetic testing and genotype--phenotype correlations - Elfride De Baere, Ludwine Messiaen Treatment of monogenic disorders - Maria Descartes, Joseph R. Biggio, Jr Tutorial: carrier screening - Wayne W. Grody, Jean A. Amos Tutorial: Gene identification in common disorders - Mark O. Goodarzi, Jerome I. Rotter Uses of databases - Roberta A. Pagon Familial adenomatous polyposis - Madhuri R. Hegde, C. Sue Richards The physical examination in clinical genetics - Marni J. Falk, Nathaniel H. Robin Genetic counseling process - Gretchen H. Schneider Cancer genetics - Katherine A. Schneider, Kelly J. Branda, Anu B. Chittenden, Kristen M. Shannon Prenatal aneuploidy screening - Katharine D. Wenstrom The microdeletion syndromes - Jodi D. Hoffman, Elaine H. Zackai Gene Therapy id number >> Section Editor: Olivier Danos, Genthon, Evry, France Gene therapy I: principles and clinical applications - J. Wesley Ulm Gene therapy II: Viral vectors and treatment modalities - J. Wesley Ulm Gene therapy in the central nervous system - Maria G. Castro, Pedro R. Lowenstein, Shyam Goverdhana Haematopoietic stem cell gene therapy - Adrian J. Thrasher, Fabio Cotti Cardiovascular gene therapy - Shalini Bhardwaj, Himadri Roy, Seppo Ylä-Herttuala Gene transfer vectors as medicinal products: risks and benefits - Christian J. Buchholz, Klaus Cichutek Immunity and tolerance induction in gene therapy - Jean Davoust Artificial self-assembling systems for gene therapy - Pierre Lehn Adenovirus vectors - Monika Lusky Adeno-associated viral vectors: depend(o)ble stability - Richard O. Snyder Retro/lentiviral vectors - Douglas E. Brown, Andrew M. L. Lever Control of transgene expression in mammalian cells - Beat P. Kramer, Martin Fussenegger Gene transfer to skeletal muscle - Jeffrey S. Chamberlain Gene transfer to the liver - Katherine P. Ponder Gene transfer to the skin - Laurent Gagnoux-Palacios, Flavia Spirito, Guerrino Meneguzzi