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The first annual Wiley Prize in Biomedical Sciences was awarded to:

Dr. H. Robert Horvitz
Massachusetts Institute of Technology
        and
Dr. Stanley J. Korsmeyer
Dana Farber Cancer Institute.

Dr. Horvitz was selected for his seminal research on programmed cell death and the discovery that a genetic pathway accounts for the programmed cell death within an organism. Dr. Korsmeyer was chosen for his discovery of the relationship between human lymphomas and the fundamental biological process of apoptosis.


Dr. H. Robert Horvitz, of the Massachusetts Institute of Technology and a recipient of the first annual Wiley Prize in Biomedical Sciences, has been selected as a recipient of the 2002 Nobel Medicine Prize.

Dr. Horvitz was named as a Nobel laureate with South African-born Sydney Brenner, of the Molecular Sciences Institute in Berkeley, California, and Sir John Sulston, of Sanger Center in Cambridge, United Kingdom, for their work on how genes regulate organ development and cell death. Dr. Horvitz was awarded the Wiley Prize earlier this year, with Dr. Stanley J. Korsmeyer of the Dana Farber Cancer Institute, for their seminal research in defining the genetic and molecular basis of programmed cell death



The second annual Wiley Prize in Biomedical Sciences was awarded to an international group of investigators:

Dr. Andrew Z. Fire
Carnegie Institution of Washington
and the Johns Hopkins University

Dr. Craig C. Mello
University of Massachusetts Medical School

Dr. Thomas Tuschl
The Rockefeller University
(formerly of the Max-Planck Institute for Biophysical Chemistry in Goettingen, Germany

          and

Dr. David Baulcombe
Sainsbury Laboratory at the John Innes Centre in Norwich, England



This year's awardees were recognized for their respective contributions to discoveries of novel mechanisms for regulating gene expression by small interfering RNAs (siRNA).

Dr. File and Dr. Mello are 2006 Nobel Laureates in Physiology or Medicine.



The third annual Wiley Prize in Biomedical Sciences was awarded to:

C. David Allis, Ph.D.
Joy and Jack Fishman Professor
Laboratory of Chromatin Biology and Epigenetics
The Rockefeller University
New York, NY
(formerly Harry F. Byrd, Jr. Professor of Biochemistry and Molecular Biology at the University of Virginia Health System)



Dr. Allis is being recognized for his significant discovery that transcription factors can enzymatically modify histones to regulate gene activity. His work is integral to understanding the genetic mechanisms behind tumor growth and has already led to breakthroughs in the treatment of certain leukemias and holds promise for many other forms of cancer.



The fourth annual Wiley Prize in Biomedical Sciences is awarded to:

Dr. Peter Walter
Howard Hughes Medical Institute Investigator
and Professor and Chairman of the Department of Biochemistry & Biophysics
University of California in San Francisco

   and

Dr. Kazutoshi Mori
Professor of Biophysics
Graduate School of Science
Kyoto University, Japan




Dr. Walter and Dr. Mori were selected as this year's recipients of the Wiley Prize in Biomedical Sciences for their discovery of the novel pathway by which cells regulate the capacity of their intracellular compartments to produce correctly folded proteins for export



The fifth annual Wiley Prize in Biomedical Sciences is awarded to:

Dr. Elizabeth H. Blackburn
Morris Herztein Professor of Biology and Physiology
Department of Biochemistry and Biophysics
University of California, San Francisco

   and

Dr. Carol Greider
Daniel Nathans Professor and
Director of Molecular Biology & Genetics
Johns Hopkins University



Dr. Blackburn and Dr. Greider were chosen for their discovery of telomerase, the enzyme that maintains chromosomal integrity. Telomerase protects against the progressive loss of genetic information during normal DNA replication, thereby helping to extend the lifetime of cells by increasing the number of times cell division can take place.

Dr. Blackburn and Dr. Greider are the first women to receive the Wiley Prize in its five-year history.


Winners of
The Wiley Prize in Biomedical Sciences


First Annual Winners

Dr. H. Robert Horvitz
Dr. Stanley J. Korsmeyer

Second Annual Winners

Dr. Andrew Z. Fire
Dr. Craig C. Mello
Dr. Thomas Tuschl
Dr. David Baulcombe

Third Annual Winner

Dr. C. David Allis

Fourth Annual Winners

Dr. Peter Walter
Dr. Kazutoshi Mori

Fifth Annual Winners

Dr. Elizabeth H. Blackburn
Dr. Carol Greider


More about current year winners...






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