Essential Resources in Influenza

New Page 2
Skin Matters

Essential Resources from Wiley-Blackwell on Influenza

Fears about Swine Flu and facts on the best methods of preventing its spread are sweeping the globe like wildfire. Is stocking Tamiflu the best option? Do facemasks work? Is it enough to constantly wash our hands, or should we not leave the house? 
Below is a FREE selection of peer-reviewed articles from Wiley-Blackwell, the publishing partner of the best academic and clinical medical associations and organizations, on the prevention, diagnosis, treatment and history of Influenza to help you better understand and address the new H1N1 virus, or deal with seasonal flu.
Cochrane Reviews The Hospitalist Influenza and Other
Respiratory Viruses
Essential Reading Essential Evidence Plus:

Be sure to read our essential selection of articles and reviews on Influenza (below) all made FREE TO ALL 

Cochrane Reviews on the prevention and treatment of Influenza

The Cochrane Library, viewed as the Gold Standard in Evidence Based Medicine, has 17 systematic reviews available on the prevention and treatment of influenza. All are available on www.thecochranelibrary.com and have been made free to enable everyone in the world with access to the internet to view the evidence and the answers for themselves.

“People making policy and taking decisions need reliable evidence, never more so than when facing a potential pandemic - Cochrane Reviews play a key role in compiling and disseminating this evidence, making it easier for people to make the best decisions about preventing and treating influenza.”

Professor Mike Clarke, Director of the UK Cochrane Centre

Read all 17 reviews FREE TO ALL
Download 3 special podcasts on influenza FREE TO ALL
Pandemic Preparation - New York City hospitalists gear up to treat, contain swine flu patients

From the Hospitalist

Drs. Novotny (MD, associate director of the hospitalist program at BIMC NY) and Rizk (DO, FHM, director of the hospitalist program at BIMC NY) suggest hospitalists follow these swine flu preparation tips:

• Communicate. Keep nurses and other staff up to date about the latest treatment and containment guidelines.
• Establish expectations. Be aware that staffers are looking to hospitalists for guidance during this emergency situation.
• Monitor for updates. Stay informed through your infectious disease division, the CDC, the WHO, and your local public health department.
Read the complete article

Pandemic study of 1918-1919 outbreak provides background and death rates for 14 European countries

From Influenza and Other Respiratory Viruses

A French study of the 1918-1919 influenza pandemic, which analysed mortality rates in approximately three-quarters of the European population, has concluded that it is unlikely that the virus, often described as Spanish Flu, originated in Europe.
The study, carried out by a team from INSERM, the French National Institute for Health and Medical Research, provides invaluable background briefing for clinicians and media during the current pandemic alert.

Read the complete press release and summary of this article

Read the complete research article FREE TO ALL
Essential Reading

Recent articles on Influenza from key Wiley-Blackwell journals – FREE TO ALL

Evaluation of twenty rapid antigen tests for the detection of human influenza A H5N1, H3N2, H1N1, and B viruses
Janette Taylor, Kenneth McPhie, Julian Druce, Chris Birch, Dominic E. Dwyer
Journal of Medical Virology
, Volume 81, Issue 11, Date: November 2009, Pages: 1918-1922

Surveillance and oseltamivir resistance of human influenza a virus in Turkey during the 2007-2008 season
Meral Akcay Ciblak, Mustafa Hasoksuz, Vanessa Escuret, Martine Valette, Fadime Gul, Huseyin Yilmaz, Nuri Turan, Emel Bozkaya, Selim Badur
Journal of Medical Virology, Volume 81, Issue 9, Date: September 2009, Pages: 1645-1651

Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics of the hemagglutinin gene

Sheng-Fan Wang, Yuan-Ming Lee, Yu-Jiun Chan, Hsin-Fu Liu, Yung-Fong Yen, Wu-Tse Liu, Jason C. Huang, Yi-Ming Arthur Chen
Journal of Medical Virology, Volume 81, Issue 8, Date: August 2009, Pages: 1457-1470

Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: A randomized placebo-controlled trial
Herman J.M. Cools, Jacobijn Gussekloo, Joyce E.M. Remmerswaal, Ed J. Remarque, Aloys C.M. Kroes
Journal of Medical Virology, Volume 81, Issue 5, Date: May 2009, Pages: 908-914

A Major Concern for Pregnant Women
Amy Labant, Julia A. Greenawalt
Nursing for Women's Health

The fight against new types of influenza virus
Biotechnology Journal, Volume 1 Issue 12Pages 1381 – 1392

Influenza type A in humans, mammals and birds: Determinants of virus virulence, host-range and interspecies transmission
Volume 25 Issue 7Pages 657 – 671

Antiviral effects of Glycyrrhiza species
Phytotherapy Research, Volume 22 Issue 2Pages 141 – 148

Influenza outbreaks
Paul S. Wikramaratna, Sunetra Gupta
Cellular Microbiology - Early View, Date: May 2009

An Improvised Oxygen Supply System for Pandemic and Disaster Use
Charles M. Little, Mark Merritt, Allen Wentworth
Academic Emergency Medicine - Early View, Date: April 2009

Effect of rapid influenza testing on the clinical management of paediatric influenza
Lance C. Jennings et al.
Influenza and Other Respiratory Viruses - Volume 3, Issue 3, Date: May 2009, Pages: 91-98

Assessing Infection Control Measures for Pandemic Influenza
Lawrence M. Wein, Michael P. Atkinson
Risk Analysis - Early View, Date: April 2009

Near-patient assays for diagnosis of influenza virus infection in adult patients
C. Steininger, M. Redlberger, W. Graninger, M. Kundi, T. Popow-Kraupp
Clinical Microbiology and Infection - Volume 15, Issue 3, Date: March 2009, Pages: 267-273

Seasonal and pandemic influenza surveillance considerations for constructing multicomponent systems
Lynnette Brammer, Alicia Budd, Nancy Cox
Influenza and Other Respiratory Viruses - Volume 3, Issue 2, Date: March 2009, Pages: 51-58

Managing public health crises: the role of models in pandemic preparedness
Seyed M. Moghadas, Nick J. Pizzi, Jianhong Wu, Ping Yan
Influenza and Other Respiratory Viruses - Volume 3, Issue 2, Date: March 2009, Pages: 75-79

Economic Evaluation of Influenza Pandemic Mitigation Strategies in the United States Using a Stochastic Microsimulation Transmission Model
Beate Sander et al.
Value in Health - Volume 12, Issue 2, Date: March/April 2009, Pages: 226-233

Viral kinetics and exhaled droplet size affect indoor transmission dynamics of influenza infection
S. C. Chen, C. P. Chio, L. J. Jou, C. M. Liao
Indoor Air - Early View, Date: February 2009

Death and serious illness following influenza vaccination: a multidisciplinary investigation
Alison Rue-Cover et al.
Pharmacoepidemiology and Drug Safety - Early View

Should Health-Care Providers in the United States Have Access to Influenza Vaccines Formulated for the Southern Hemisphere?
Raymond A. Strikas, Phyllis E. Kozarsky, Christie Reed, Brian K. Kapella, David O. Freedman
Journal of Travel Medicine - Volume 15, Issue 6, Date: November/December 2008, Pages: 442-446

Comparing the antibody responses against recombinant hemagglutinin proteins of avian influenza A (H5N1) virus expressed in insect cells and bacteria
Shuo Shen et al.
Journal of Medical Virology - Volume 80, Issue 11, Date: November 2008, Pages: 1972-1983

Lack of cross-immune reactivity against influenza H5N1 from seasonal influenza vaccine in humans
Julian W. Tang, Karry L.K. Ngai, Paul K.S. Chan
Journal of Medical Virology - Volume 80, Issue 11, Date: November 2008, Pages: 1992-1996

Acute necrotizing encephalopathy: A comparison between influenza and non-influenza cases

Akihisa Okumura, Sinpei Abe, Hiroyuki Kidokoro and Masashi Mizuguchi
Microbiology and Immunology - Volume 53 Issue 5, Pages 277 - 280

Pandemic influenza and the hospitalist: Apocalypse when?
James C. Pile, Steven M. Gordon
Journal of Hospital Medicine - Volume 1, Issue 2, Date: March/April 2006, Pages: 118-123


Title logo or cover image

Reviews of Economic Evaluations relating to Influenza

From HEED: Health Economics Evaluation Database

Read more the 15 article reviews - FREE TO ALL

Book chapters from key Wiley-Blackwell titles

Infectious Disease Surveillance
Nkuchia M. M'ikanatha (Editor), Ruth Lynfield (Editor), Chris A. Van Beneden (Editor), Henriette de Valk (Editor)
September 2007
CHAPTER 19: Seasonal and pandemic influenza surveillance
Lynnette Brammer, Alicia Postema & Nancy Cox
Tropical Diseases in Travelers
Eli Schwartz
June 2009
CHAPTER 41: Travel-related respiratory infections
Eyal Meltzer and Eli Schwartz
Essential Evidence Plus: Daily POEMS

Characteristics of patients with H1N1 influenza

Clinical Question:
What are the typical presenting symptoms of patients with the novel H1N1 influenza initially detected in April 2009?

Bottom Line:
The initial outbreak of H1N1 influenza was characterized by symptoms similar to those seen in patients with seasonal influenza and by a low overall mortality. A very large number of patients with a mild form of the illness were likely not diagnosed. (LOE = 3b)

Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team, Dawood FS, Jain S, et al. Emergence of a novel swine-origin influenza A (H1N1) virus in humans. N Engl J Med 2009;360(25):2605-2615.

Swine influenza viruses contain genes from human, swine, and avian influenza A viruses. A new variant of influenza A (H1N1) was initially detected in April, 2009, and has gone on to cause a worldwide pandemic. This report describes the characteristics of the first 642 cases identified in 41 states. The median age of patients was 20 years, with a range of 3 months to 81 years; 40% of patients were between the ages of 10 to 18 years, and 35% between 19 and 50 years. Patients presented with fever (94%), cough (92%), sore throat (66%), diarrhea (25%), and vomiting (25%); data were available regarding symptoms for 50% to 66% of patients, depending on the symptom. Hospitalization status was known for 399 patients, of whom 9% were hospitalized, with an age range of 19 months to 51 years. Many of the hospitalized patients had chronic medical conditions. The virus was sensitive to both oseltamivir and zanamivir. At the time of this writing (June 30, 2009) the CDC reported 27,717 confirmed or probable cases and 127 deaths (0.4%).