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Diffusion Tensor Imaging H-1 Glutamate Human Brain Restricted Diffusion Diffusion Rat-Brain NMR Metabolism Metabolomics Quantification Mice Multiple-Sclerosis Glutamine Spectra T-2 Relaxation Mouse Spin-Echo Brain Model Magnetic-Resonance-Spectroscopy Spectroscopy Choline White-Matter H-1 MRS In-Vivo MRI Contrast Agents Water Diffusion Tissue