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The Model Legume Medicago truncatula




The Model Legume Medicago truncatula

Frans J. de Bruijn

ISBN: 978-1-119-40916-8 November 2019 Wiley-Blackwell 1328 Pages


Fully covers the biology, biochemistry, genetics, and genomics of Medicago truncatula

Model plant species are valuable not only because they lead to discoveries in basic biology, but also because they provide resources that facilitate translational biology to improve crops of economic importance. Plant scientists are drawn to models because of their ease of manipulation, simple genome organization, rapid life cycles, and the availability of multiple genetic and genomic tools. This reference provides comprehensive coverage of the Model Legume Medicago truncatula. It features review chapters as well as research chapters describing experiments carried out by the authors with clear materials and methods. Most of the chapters utilize advanced molecular techniques and biochemical analyses to approach a variety of aspects of the Model.

The Model Legume Medicago truncatula starts with an examination of M. truncatula plant development; biosynthesis of natural products; stress and M. truncatula; and the M. truncatula-Sinorhizobium meliloti symbiosis. Symbiosis of Medicago truncatula with arbuscular mycorrhiza comes next, followed by chapters on the common symbiotic signaling pathway (CSSP or SYM) and infection events in the Rhizobium-legume symbiosis. Other sections look at hormones and the rhizobial and mycorrhizal symbioses; autoregulation of nodule numbers (AON) in M. truncatula; Medicago truncatula databases and computer programs; and more.

  • Contains reviews, original research chapters, and methods
  • Covers most aspects of the M. truncatula Model System, including basic biology, biochemistry, genetics, and genomics of this system
  • Offers molecular techniques and advanced biochemical analyses for approaching a variety of aspects of the Model Legume Medicago truncatula
  • Includes introductions by the editor to each section, presenting the summary of selected chapters in the section
  • Features an extensive index, to facilitate the search for key terms

The Model Legume Medicago truncatula is an excellent book for researchers and upper level graduate students in microbial ecology, environmental microbiology, plant genetics and biochemistry. It will also benefit legume biologists, plant molecular biologists, agrobiologists, plant breeders, bioinformaticians, and evolutionary biologists.

Explanation of the flow of Chapters.

The first Chapter will be an Introduction to the Book by the Editor, giving the background to the field, and its aims. Section 2 will contain two general reviews on the History, Evolution and Agronomic use of M. truncatula, and the second one on the Use of M. truncatula as a Legume Model System.  Section 3 will cover basic aspects of M. truncatula seed development, root development, leaf development and flower development. Section 4 will discuss the biosynthesis of natural products by M. truncatula. Section 5 will cover the responses of M. truncatula to abiotic and biotic stresses, such as salt and drought stress, root pathogens (such as Aphanomyces), aphids, pathogenic bacteria, and other pathogens (such as  Orobanche crenata, rust pathogens and wilt).  Section 6 will introduce the M. truncatula-S. rhizobium symbiosis and biological nitrogen fixation in legumes, followed by signalling and early infection events.  Section 7 will address the symbiosis between M. truncatula and arbuscular mycorrhizal fungi, followed by signalling and infection events.  Section 8 will introduce the common signalling pathway (CSSP or SYM) between rhizobia and arbuscular mycorrhizal infections.  Section 9 will cover the role of hormones in both type of symbioses.  Section 10 will address the phenomenon of Autoregulation Of Nodule numbers in M. truncatula (AON). Section 11 will discuss late infection events in the Rhizobium-Legume symbiosis, including infection thread development, bacterial release, formation of symbiosomes and bacteroids and the role of Nodule-specific Cysteine-Rich  (NCR) peptides, as well as bacteroid functioning, bacteroid senescence and the structure of indeterminate M. truncatula nodules. Section 12 will cover transposons, gene instability and gene tagging in M. truncatula. Section 13 introduces the genetics of M. truncatula with a sequence-based genetic map of M. truncatula and Quantitative Trait Loci mapping (QTL) in this organism, as well as Genome-Wide Association Studies (GWAS).  Section 14 addresses the Genomics of M. truncatula, including the Genome Sequence of M. truncatula, genome Evolution, translational genomics, small RNA’s in M. truncatula, Genomic and Genetic Markers in M. truncatula, Mutagenesis, forward and reverse Genetics, Transcriptomics, Proteomics and Phosphoproteomics, as well as Metabolomics in M. truncatula.  This section ends with a listing of Databases and Computer Programs useful for M. truncatula. Section 15 briefly deals with M. truncatula transformation.  Section 16 (Appendix) proposes guidelines for genetic nomenclature and community governance for M. truncatula.