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The Embryonic Human Brain: An Atlas Of Developmental Stages, 3rd Edition

The Embryonic Human Brain: An Atlas Of Developmental Stages, 3rd Edition

Ronan R. O'Rahilly, Fabiola Müller

ISBN: 978-0-471-97308-9 October 2005 512 Pages



The new edition of The Embryonic Human Brain: An Atlas of Developmental Stages represents the integration of analysis of the serial sections of human embryos in the Carnegie collection with results of the latest ultrasound studies. It provides summaries of the morphological status of the brain at each stage of development, covering both normal and anomalous conditions. Preceding the atlas are several chapters that present historical aspects, techniques, and prenatal measurements, as well as an introduction to embryonic staging, and terminology accompanied by over definitions of key terms.
  • Now illustrated in full colour throughout
  • Includes high quality photographs, photomicrographs, and diagrams
  • Expands coverage of magnetic resonance imaging of the fetal and perinatal periods
  • Highlights molecular and genetic aspects of normal and abnormal development of the brain
  • Utilizes a set of standardized abbreviations
  • Provides selected references to seminal studies

Review for the Second Edition:

"[A] really beautiful and wonderfully informative book that no embryologist, comparative anatomist, pediatric neurologist or neurosurgeon should be without. Putting aside the medical relevance of this atlas, it also provides the most captivating version of one of the most complex and fascinating embryological stories of all.”  BRAIN

This atlas is an invaluable resource for neuroscientists, developmental biologists, comparative anatomists, neurologists, pathologists, radiologists, and neurosurgeons.

Preface to the Third Edition.

1. Historical Aspects.

2. Techniques.

3. Prenatal Measurements.

4. Embryonic Staging.

5. Prenatal Age.

6. Terminology.

7. Early Stages.

8. Stage 8: The First Appearance of the Nervous System.

9. Stage 9: The Major Divisions of the Brain.

10. Stage 10: The Neural Tube and the Optic Primordium.

11. Stage 11: Closure of the Rostral Neuropore.

12. Stage 12: Closure of the Caudal Neuropore and the Beginning of Secondary Neurulation.

13. Stage 13: The Closed Neural Tube and the First Appearance of the Cerebellum.

14. Stage 14: The Future Cerebral Hemispheres.

15. Stage 15: Longitudinal Zoning in the Diencephalon.

16. Stage 16: Evagination of the Neurohypophysis.

17. Stage 17: The Future Olfactory Bulbs and the First Amygdaloid Nuclei.

18. Stage 18: The Future Corpus Striatum, the Inferior Cerebellar Peduncles, and the Dentate Nucleus.

19. Stage 19: The Choroid Plexus of the Fourth Ventricle and the Medial Accessory Olivary Nucleus.

20. Stage 20: The Choroid Plexus of the Lateral Ventricles, the Optic and Habenular Commissures, and the Interpeduncular and Septal Nuclei.

21. Stage 21: The First Appearance of the Cortical Plate in the Cerebral Hemispheres.

22. Stage 22: The Internal Capsule and the Olfactory Bulbs.

23. Stage 23: The Brain at the End of the Embryonic Period.

24. Trimester 1, Postembryonic Phase.

Early Postembryonic Phase.

Later Postembryonic Phase.

25. Trimester 2.

26. Trimester 3 and the Newborn.

Supplement: Early Postnatal Life.



Appendix 1: Changing Lengths of the Brain and its Subdivisions from 31/2 to 51/2 Weeks (Stages 9–16).

Appendix 2: Computer Ranking of the Sequence of Appearance of Features of the Brain.

Appendix 3: Sequence and Stage of Appearance of Median Features of the Brain

Appendix 4: Sequence and Stage of Appearance of Tracts of the Brain.

Appendix 5: Sequence and Stage of Appearance of Features Associated with the Rhombencephalon.


"…a unique resource that provides an outstanding reference for investigators…and for physicians…" (Doody's Book Reviews)