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The AST Handbook of Transplant Infections




The AST Handbook of Transplant Infections

Deepali Kumar, Atul Humar

ISBN: 978-0-470-65827-7 May 2011 Wiley-Blackwell 188 Pages


Whether you need to manage a post-transplant infection or reduce the possibility of infection, you will find effective guidance in this handbook. The work of the American Society of Transplantation Infectious Diseases Community of Practice, this reference exclusively uses tables and flowcharts to speed up decision making.

This distinguished group of investigators and teachers provide point of care information on optimum management of infection in adult and pediatric organ and stem cell transplant patients.  The unique tables and flowcharts are devised by the authors, backed up with extensive references, making the book a fully researched yet easy to use guide.  

The fast growing specialty of transplantation will be well served by this book as increasing numbers of successful procedures mean transplant teams have to be ever more alert to the possibility of and need for action in the event of ensuing infection.

Part 1 General Issues and Infectious Syndromes.

1 Timeline of Infections After Organ Transplant (Christian van Delden).

2 Timeline of Infections After Hematopoietic Stem Cell Transplant (Sarah P. Hammond & Francisco M. Marty).

3 Immune Reconstitution After Myeloablative Stem Cell Transplant (Sarah P. Hammond & Francisco M. Marty).

4 Pre-transplant Infectious Disease Evaluation of the Organ Transplant Candidate (Staci A. Fischer).

5 Pre-transplant Infectious Disease Evaluation of the Hematopoietic Stem Cell Transplant Candidate (Staci A. Fischer).

6 Technical Complications after Organ Transplant and Associated Infections (Abhinav Humar).

7 Evaluation and Initial Treatment of Infectious Complications Among Organ Transplant Recipients (Kathleen Julian).

8 Management of Infections in Kidney Transplant Recipients (Bartholomew Bono).

9 Management of Infections in Pancreas Transplant Recipients (Bartholomew Bono).

10 Management of Infections in Liver Transplant Recipients (Bartholomew Bono).

11 Management of Infections in Lung, Heart–Lung, and Heart Transplant Recipients (Shahid Husain & S.M. Hosseini-Mogaddham).

12 Management of Infections in Intestinal Transplant Recipients (Michael Green).

13 Antimicrobial Management of Patients with Fever and Neutropenia Following Hematopoietic Stem Cell Transplantation (Upton D. Allen).

Part II Specific Pathogens.

14 Cytomegalovirus (Raymund R. Razonable & Atul Humar).

15 Epstein-Barr Virus and Post-transplant Lymphoproliferative Disorders (Rebecca Madan & Betsy Herold).

16 Management of herpes simplex virus (Marian G. Michaels).

17 Management of Varicella Zoster Virus (Marian G. Michaels).

18 Prevention and Treatment of Human Herpesvirus 6, 7 and 8 Infections in Transplant Recipients (Raymund R. Razonable).

19 BK Polyomavirus and Polyomavirus-associated Nephropathy (Hans H. Hirsch).

20 Respiratory Viruses (Oriol Manuel).

21 Human Papillomavirus (Gail E. Reid).

22 Hepatitis B (Karen E. Doucette).

23 Hepatitis C Management in Transplant Candidates and Recipients (Karen E. Doucette).

24 Management Algorithm for Transplantation in Patients with Human Immunodeficiency Virus (Shirish Huprikar).

25 Management of Selected Fungal Infections After Transplantation (Michele I. Morris).

26 Treatment of Nocardia). Infections (Nina M. Clark).

27 Tuberculosis: Treatment and Prevention (Nina M. Clark).

28 Treatment of Non-tuberculous Mycobacterium). Infections (Nina M. Clark).

29 Pneumocystis jiroveci). Pneumonia: Prophylaxis and Therapy (Nicolas J. Mueller).

30 Suggested Therapy of Clostridium diffi cile). Colitis After Transplantation (Aneesh K. Mehta).

31 Diagnosis and Treatment of Multidrug-Resistant Bacteria (Emily A. Blumberg).

32 Management of Selected Parasitic Infections After Transplant (Sanjay Mehta & Robert Huang).

Part III Donor Issues.

33 Infectious Disease Evaluation of the Potential Organ Donor (Staci A. Fischer).

34 Infectious Disease Evaluation of the Potential Hematopoietic Stem Cell Transplant Donor (Staci A. Fischer).

35 Donor-derived Infections (Michael G. Ison).

36 Estimates of Window Period Length for Serology and Nucleic Acid Testing (Atul Humar).

37 Estimates of Residual Risk of HIV or HCV when using Selected Increased Risk Donor Categories (Atul Humar).

38 Management of Recipients of Hepatitis B Core Antibody-Positive Donor Organ (Karen E. Doucette).

39 Donor Tuberculosis Issues: Potential Scenarios and Management (Camille N. Kotton & Michele I. Morris).

Part IV Prevention of Infections after Transplantation.

40 Suggested Prophylaxis Regimens in Organ Transplant Recipients (Nasia Safdar, Germana L.M. Silva & Jennifer Hsu).

41 Antimicrobial Prophylaxis Regimen for Allogeneic Hematopoietic Stem Cell Transplant Recipients (Sherif Mossad).

42 Antimicrobial Prophylaxis Regimen for Autologous Hematopoietic Stem Cell Transplant Recipients (Sherif Mossad).

43 Adult Vaccination Schedule After Solid Organ Transplant (Marissa Wilck & Lindsey Baden).

44 Adult Vaccination Schedule After Allogeneic Stem Cell Transplant (Lindsey Baden & Marissa Wilck).

45 Immunizations After Pediatric Solid Organ Transplant and Hematopoietic Stem Cell Transplant (Tanvi Sharma & Lynne Lewis).

46 Recommendations for Travel-related Vaccinations and Medications for Transplant Travelers (Camille N. Kotton).

47 Safe Living Strategies for Transplant Patients (Julia Garcia-Diaz & Shannon Bergeron).

Part V Post-transplant Medications and Drug Interactions.

48 Common Immunosuppressive Drugs, Mechanisms of Action, Side-effects, and Other Interactions (Daniel Kaul).

49 Infectious Risks Associated with Anti-thymocyte Globulin (ATG,Thymoglobulin) (Steven D. Burdette).

50 Infectious Risks Associated with Alemtuzumab (Campath) (Steven D. Burdette).

51 Infectious Risks Associated with IL-2R Antagonist [Basiliximab (Simulect) and Daclizumab (Zenapax)] (Steven D. Burdette).

52 Infectious Risks Associated With Rituximab (Rituxan) (Steven D. Burdette).

53 Drug Interactions Between Antimicrobial Agents and Common Immunosuppressive Drugs Used in Transplantation (Christian Garzoni).

54 Antiviral Agents for Adult Transplant Recipients (Valentina Stosor).

55 Antifungal Agents in Adult Transplant Recipients (Shmuel Shoham).

56 Antiviral Agents for Pediatric Transplant Recipients (Lara Danziger-Isakov, Lizbeth Hansen & Elizabeth Neuner).

57 Antifungal Agents for Pediatric Transplant Recipients (Lara Danziger-Isakov, Lizbeth Hansen & Elizabeth Neuner).

"Overall, I enjoyed this book and its contribution to the field of transplantation. Many clinicians would find this helpful in their daily practice." (Doody's, 16 December 2011)