DescriptionThe importance of early prevention and treatment of sepsis has never been greater. In the UK alone sepsis contributes to more deaths than lung cancer, from bowel cancer and breast cancer combined, and approximately one third of patients who suffer from severe sepsis die. The ABC of Sepsis provides a much needed introduction and an invaluable aid in the increasing efforts to reduce hospital infection and improve patient safety.
As growing numbers of junior medical staff experience emergency medicine, critical care and acute medicine as part of the Foundation Programme, there is an increasing need to develop the skills required to treat severe sepsis. The editors are involved with the Survive Sepsis campaign - developed to improve the recognition, diagnosis and treatment of sepsis - and are perfectly placed to guide junior medics, GPs, specialist nurses, critical care nurses and primary care staff through this core aspect of acute medicine.
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1 Introduction 1
Mitchell M. Levy
2 Defining the Spectrum of Disease 5
3 Identifying the Patient with Sepsis 10
4 Serious Complications of Sepsis 15
Hentie Cilliers Tony Whitehouse and Bill Tunnicliffe
5 The Pathophysiology of Sepsis 20
Edwin Mitchell and Tony Whitehouse
6 Initial Resuscitation 25
7 Microbiology and Antibiotic Therapy 29
Partha De and Ron Daniels
8 Infection Prevention and Control 36
Fiona Lawrence Georgina McNamara and Clare Galvin
9 The Role of Imaging in Sepsis 42
10 Presentations in Medical Patients 48
11 Presentations in Surgical Patients 57
Jonathan Stewart and Sian Abbott
12 Special Cases: The Immunocompromised Patient 62
13 The Role of Critical Care 68
14 Monitoring the Septic Patient 73
15 Novel Therapies in Sepsis 78
Gavin D. Perkins and David R. Thickett
16 Approaches to Achieve Change 83
Julian F. Bion and Gordon D. Rubenfield
- A much needed introduction to this important subject - a core aspect of acute medicine in the UK.
- Offers a basic introduction to sepsis for trainees and the MDT – a core aspect of acute medicine
- A timely subject due to current concerns regarding hospital infection and patient safety
- The authors are involved with the Surviving Sepsis campaign, developed to improve the management, diagnosis and treatment of sepsis