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Antibiotics and Antibiotic Resistance

Ola Sköld

ISBN: 978-1-118-07560-9 November 2011 224 Pages


This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance poses for medicinal and drug-related fields, and perhaps trigger more research and discoveries to fight antibiotic resistant strains.

Current overviews of the topic are included, along with specific discussions on the individual mechanisms (betalactams, glycopeptides, aminoglycosides, etc) used in various antibacterial agents and explanations of how resistances to those develop. Methods for counteracting resistance development in bacteria are discussed as well.

1. Antibiotics, the Greatest Triumph of Scientific Medicine.

2. Distribution of Antibiotics.

3. Sulfonamides and Trimethoprim.

4. Betalactams.

5. Glycopeptides.

6. Aminoglycosides.

7. Further Antibiotics Interfering with Bacterial Protein Synthesis.

8. Quinolones.

9. Antibacterial Agents that are not Related to the Large Antibiotic Families.

10. Mechanisms for the Horizontal Spread of Antibiotic Resistance Among Bacterial.

11. How to Handle Resistance Against Antibiotics?

“This is a good book with good information about antibiotics. It fits nicely in the pocket of a laboratory coat and could be carried around by physicians. It concludes with a serious message -- that we have enjoyed the use of antibiotics on a "loan from nature," and this loan is expiring with a "threat of foreclosure.”  (Doody’s, 6 April 2012)