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Asymmetric Synthesis of Nitrogen Heterocycles

Asymmetric Synthesis of Nitrogen Heterocycles

Jacques Royer (Editor), H. P. Husson (Foreword by)

ISBN: 978-3-527-62550-5

Aug 2009

425 pages

Description

Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications.
Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.
PART 1: Asymmetric Synthesis of Nitrogen Heterocycles Containing Only One Heteroatom

ASYMMETRIC SYNTHESIS OF THREE- AND FOUR-MEMBERED RING HETEROCYCLES
Substituted Aziridines
Substituted Monocyclic Azetidines and Carbocyclic-Fused Systems
ASYMMETRIC SYNTHESIS OF FIVE-MEMBERED RING HETEROCYCLES
Monocyclic Pyrrolidines and Pyrrolidinones
Pyrrolines
Fused Bicyclic Systems with Bridgehead Nitrogen
ASYMMETRIC SYNTHESIS OF SIX-MEMBERED RING HETEROCYCLES
Introduction
Dihydropyridines
Tetrahydropyridines
Monocyclic Piperidines and Carbocyclic Fused Systems
Fused Tri- or Bicyclic System with Bridgehead Nitrogen
ASYMMETRIC SYNTHESIS OF SEVEN- AND MORE-MEMBERED RING HETEROCYCLES
Substituted Azepines
Substituted Azocines
Substituted Large Nitrogen-Containing Rings

PART 2: Asymmetric Synthesis of Nitrogen Heterocycles With More Than One Heteroatom

ASYMMETRIC SYNTHESIS OF THREE- AND FOUR-MEMBERED RING HETEROCYCLES WITH MORE THAN ONE HETEROATOM
Introduction
Three-Membered N-Heterocycles with Two Heteroatoms
Four-Membered N-Heterocycles with Two Heteroatoms
ASYMMETRIC SYNTHESIS OF FIVE-MEMBERED RING HETEROCYCLES WITH MORE THAN ONE HETEROATOM
Five-Membered Heterocycles with N and O Atoms
Five-Membered Heterocycles with Two N Atoms
Five-Membered Heterocycles with N and S Atoms
ASYMMETRIC SYNTHESIS OF SIX-MEMBERED RING NITROGEN HETEROCYCLES WITH MORE THAN ONE HETEROATOM
Six-Membered Rings with Another Heteroatom in the Same Ring
ASYMMETRIC SYNTHESIS OF SEVEN-MEMBERED RINGS WITH MORE THAN ONE HETEROATOM
Diazepines
Oxazepines
Thiazepines
""Finding no book or review article offering an overview of methods used in preparation of nitrogen heterocycles in their asymmetric form, Royer (University Paris Descartes) tackled the project, enlisting contributions from some colleagues with special expertise...The volume offers a clearly structured, compact presentation in two sections."" (SciTech Book News, December 2010)

""The book is clearly written and very well structured. It should prove useful to any chemist interested in a brief overview of the main procedures for the asymmetric synthesis of simple nitrogen heterocycles."" (Angewandte Chemie International Edition, 2009)