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Bioinformatics: From Nucleic Acids and Proteins to Cell Metabolism

Bioinformatics: From Nucleic Acids and Proteins to Cell Metabolism

Dietmar Schomburg (Editor), Uta Lessel (Editor)

ISBN: 978-3-527-61519-3

Dec 2007

205 pages

Select type: O-Book

Description

Bioinformatics, in this context the application of computer science to biological problems, has become an indispensable part of any research in the biosciences. Rapid developments in gene sequencing, structure determination as well as rational protein engineering and design have made it necessary for biologists, chemists, and computer scientists to channel their expertise into large scale collaborative projects.
This GBF Monograph gives a general overview of the latest versatile activities in bioinformatics:
* Biological Data Bases
* DNA and RNA
* Protein Sequences and Structures
* From Molecules to Cell Metabolism

The articles have been selected from contributions to a conference on Bioinformatics/Computer Application in the Biosciences, held in October 1995 in Braunschweig at the German National Research Center for Biotechnology.
Partial table of contents:

BIOLOGICAL DATA BASES.

An Integrated Service Approach to Biological Sequence Databases (K. Heumann, et al.).

DNA AND RNA.

Statistical Analysis of DNA Sequences (H. Herzel, et al.).

A Consensus Match Scoring System that is Correlated with Biological Functionality (K. Quandt, et al.).

PROTEIN SEQUENCES AND STRUCTURES.

Statistical Significance of Local Alignments with Gaps (M. Vingron & M. Waterman).

An Algorithm for the Protein Docking Problem (H.-P. Lenhof).

FROM MOLECULES TO CELL METABOLISM.

Force Field Minimization: Domain Decomposition, Positive Definite Functions, and Wavelets (E. Schmitt).

Simulation and Animation of Intracellular Diffusion (H.-G. Lipinski).