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Biotechnology, A Multi-Volume Comprehensive Treatise, Volume 5B, Genomics and Bioinformatics, 2nd, Completely Revised Edition

Biotechnology, A Multi-Volume Comprehensive Treatise, Volume 5B, Genomics and Bioinformatics, 2nd, Completely Revised Edition

Christoph W. Sensen (Volume Editor), Hans-Jürgen Rehm (Editor), Gerald Reed (Editor), Alfred Pühler (Associate Editor), Peter Stadler (Associate Editor)

ISBN: 978-3-527-62087-6

Mar 2008, Wiley-Blackwell

478 pages

Select type: O-Book

Description

Genomics is a new discipline that is revolutionizing the way biological and medical research is done. The human genome is almost completely sequenced, which will help to accelerate research and development in Genomics even more. The chapters in this book try to capture the rapidly evolving field. Overviews of nucleic acid technologies, proteomics and bioinformatics are followed by chapters on applications, including human health, agriculture and comparative genomics. The book also includes two chapters on legal and ethical issues of Genomics, a topic that is becoming more and more important.
Introduction (C. Sensen).

APPLICATION DOMAINS.

Genome Projects of Model Organisms (A. Pühler, et al.).

The Human Genome Project (L. Tsui & S. Scherer).

Genetic Disease (G. Dellaire).

Genomics and Human Disease (R. Green).

Pharmaceutical Bioinformatics and Drug Discovery (C. Ramanathan & D. Davison).

Agri-Food and Genomics (I. Parkin, et al.).

DNA TECHNOLOGIES.

Genomic Mapping and Positional Cloning, with Emphasis on Plant Science (A. Vanavichit, et al.).

Sequencing Technology (L. Middendorf, et al.).

A DNA Microarrays Fabrication Strategy for Research Laboratories (D. Tessier, et al.).

PROTEIN TECHNOLOGIES.

Two-Dimensional Gels Electrophoresis and Mass Spectrometry for Proteomic Studies: State-of-the-Art (D. Figeys).

Proteome Analysis by Capillary Electrophoresis (N. Dovichi, et al.).

BIOINFORMATICS.

Using the Molecular Biology Data (E. Zdobnov, et al.).

Tools for DNA Technologies (P. Rice).

Tools for Protein Technologies (D. Wishart).

Structure Information (M. Cygler, et al.).

Automated Genome Annotation and Comparative Genomics (S. Gopal & T. Gaasterland).

Genomic Data Representation through Images - MAGPIE as an Example (P. Gordon, et al.).

Interaction Databases (G. Bader & C. Hogue).

ETHICAL, LEGAL AND SOCIAL ISSUES.

Ethical Aspects of Genome Research and Banking (B. Knoppers).

Genomics - Five Years from Now (C. Sensen).

Index.