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Biotechnology, A Multi-Volume Comprehensive Treatise, Volume 8B, Bio-transformations II, 2nd, Completely Revised Edition

Biotechnology, A Multi-Volume Comprehensive Treatise, Volume 8B, Bio-transformations II, 2nd, Completely Revised Edition

David R. Kelly (Volume Editor), Jörg Peters (Consultant), Hans-Jürgen Rehm (Editor), Gerald Reed (Editor), Alfred Pühler (Associate Editor), Peter Stadler (Associate Editor)

ISBN: 978-3-527-62091-3

Mar 2008, Wiley-Blackwell

545 pages

Select type: O-Book

Description

Biotransformations have developed into an important tool of organic synthesis and most synthetic sequences will benefit from the use of a biotransformation step. This volume completes the collection of biotransformations presented in the Biotechnology series. Volumes 8 a and b provide a comprehensive guide to the established and emerging uses of enzymes, each chapter is devoted to a single class of transformation.
The description of several bond forming reactions is followed by four chapters on structue and catalytic activity. Case studies of important industrial and synthetic applications round off the practical orientation of the book.
Introduction (D. Kelly).

CARBON-CARBON BOND FORMATION, ADDITION, ELIMINATION AND SUBSTITUTION REACTIONS.

Carbon-Carbon Bond Formation Using Enzymes (A. Curtis).

Lyases (D. Kelly & J. Mahdi).

Halocompounds (G. Robinson, et. al.).

Phosphorylation (S. Jones).

Enzymes in Carbohydrate Chemistry: Formation of Glycosidic Linkages (S. Flitsch & G. Watt).

APPLICATIONS

Industrial Biotransformations (U. Bornscheuer).

Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, A Key Reaction in the Industrial Synthesis of 1-Deoxynojirimycin (M. Schedel).

Engineering Microbial Pathways for Amino Acid Production (I. Fotheringham).

Biotechnological Production of Natural Aroma Chemicals by Fermentation Processes (J. Rabenhorst).

Synthetic Applications of Enzyme-Catalyzed Reactions (J. McGregor-Jones).

THE FUTURE OF BIOTRANSFORMATIONS

Catalytic Antibodies (G. Blackburn & A. Carçon).

Synthetic Enzymes: Artificial Pestides in Stereoselective Synthesis (P. Bentley).

Index.