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Carbohydrates in Chemistry and Biology: A Comprehensive Handbook

Carbohydrates in Chemistry and Biology: A Comprehensive Handbook

Beat Ernst (Editor), Gerald W. Hart (Editor), Pierre Sinaÿ (Editor)

ISBN: 978-3-527-61825-5 April 2008 2578 Pages

O-Book
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Description

Carbohydrate Chemistry and Glycobiology have witnessed a rapid expansion during the last few years with the development of numerous new, imaginative and efficient syntheses which provide further insight into structures and biological interactions of glycoconjugates. Glycosylation reactions are widely used in the synthesis of pharmaceuticals and bio-active compounds. In biology and medicine oligosaccharides play a central role in immuno-stimulation, cancer or allergic responses. Glycoscience is a very instructive example of how one common topic of interest stimulates both chemistry and biology to collectively open scientific frontiers.

This synergy is made visible in this work. Three leading experts in the fields of Glycochemistry and Glycobiology have invited numerous renowned authors to provide a comprehensive overview of the recent advances and findings in Glycoscience. This four-volume handbook presents an integrated and cutting-edge view, and covers all chemical aspects, such as syntheses and analysis of carbohydrates and oligosaccharides, as well as the biological role and activity of oligosaccharides and carbohydrate/protein interactions.

PART I: CHEMISTRY OF SACCHARIDES
VOLUME I:CHEMICAL SYNTHESIS OF GLYCOSIDES AND GLYCOMIMETICS
Chemical Synthesis of Glycosides
Synthesis of Oligosaccharide Mimics
VOLUME II: ENZYMATIC SYNTHESIS OF GLYCOSIDES AND CARBOHYDRATE-RECEPTOR INTERACTIONS
Enzymatic Methods for Glycosylations
Carbohydrate-Protein Interactions
Carbohydrate-Nucleic Acid Interactions
Carbohydrate-Carbohydrate Interactions
PART II: BIOLOGY OF SACCHARIDES
VOLUME III: BIOSYNTHESIS AND DEGRADATION OF GLYCOCONJUGATES
Biosynthesis of Glycoconjugates
Degradation of Glycoconjugates
VOLUME IV: LECTINS AND SACCHARIDE BIOLOGY
Lectins
Saccharide BiologyPart I: Chemistry of Saccharides
"a very useful collection of mostly excellent overviews" (Angewandte Chemie, International Edition 19 November 2001)