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Cell Adhesion and Human Disease



Cell Adhesion and Human Disease

Joan Marsh (Editor), Jamie A. Goode (Editor)

ISBN: 978-0-470-51472-6 April 2008 254 Pages


Experts in their respective fields present papers concerned with the range of human diseases caused by defective or abnormal functioning of cell adhesion molecules. Discusses new therapeutic approaches to these maladies.
Partial table of contents:

P-Selectin Knockout: A Mouse Model for Various Human Diseases (D. Wagner).

Von Willebrand's Disease and the Mechanisms of Platelet Function (Z. Ruggeri).

Leukocyte Adhesion Deficiency (LAD) II (A. Etzioni, et al.).

Adhesion Molecules in Cutaneous Inflammation (J. Barker).

Defective Cell-Cell Adhesion in the Epidermis (J. Stanley).

E-Cadherin as an Invasion Suppressor (W. Birchmeier, et al.).

The Role of CD44 Splice Variants in Human Metastatic Cancer (J. Sleeman, et al.).

Early Metastasis of Human Solid Tumours: Expression of Cell Adhesion Molecules (K. Pantel, el al.).

Treatment of Inflammatory Diseases with a Monoclonal Antibody to Intercellular Adhesion Molecule 1 (R. Rothlein & J. Jaeger).