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Cell Junctions: Adhesion, Development and Disease

Cell Junctions: Adhesion, Development and Disease

Susan E. La Flamme (Editor), Andrew P. Kowalczyk (Editor)

ISBN: 978-3-527-62210-8 August 2008 Wiley-Blackwell 318 Pages

 E-Book

$159.99

Description

This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins with an overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections.
Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.
Overview of Cellular Junctions

CELL-MATRIX JUNCTIONS
Integrin Transmembrane Signaling
Focal Adhesion
Signaling Through FAK
Focal Adhesion Dynamics
Integrin Trafficking
Hemidesmosomes
Cell Matrix Adhesion in 3 Dimensions

CELL-CELL JUNCTIONS
Epithelial Adherens Junctions
Endothelial Adherens Junctions
Gap Junctions
Tight Junctions
Desmosomes
Junctions Dynamics and Adhesion Receptor Trafficking

CELL-MATRIX AND CELL-CELL CROSSTALK
Adhesion Receptors in Mechanotransduction
Crosstalk Between Cell-Cell and Cell-Matrix Adhesion

?This volume presents an excellent overview into the world of cell adhesion. It provides important details about the main players in all aspects of cell junctions.?( The Quarterly Review of Biology , September 2009)

"This is a welcome addition to the literature that will be valued by all students of cell adhesion and morphogenesis." (Doody's, January 2009)