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Classics in Total Synthesis II: More Targets, Strategies, Methods

Classics in Total Synthesis II: More Targets, Strategies, Methods

K. C. Nicolaou , S. A. Snyder

ISBN: 978-3-527-30684-8

Oct 2003

658 pages

Select type: Paperback

In Stock

$115.00

Description

Classics in Total Synthesis II is the long awaited sequel to Classics in Total Synthesis, a book that has made its mark as a superb tool for educating students and practitioners alike in the art of organic synthesis since its introduction in 1996. In this highly welcomed new volume, K. C. Nicolaou and Scott A. Snyder discuss in detail the most impressive accomplishments in natural product total synthesis during the 1990s and the first years of the 21st century. While all of the features that made the first volume of Classics so popular and unique as a teaching tool have been maintained, in this new treatise the authors seek to present the latest techniques and advances in organic synthesis as they beautifully describe the works of some of the most renowned synthetic organic chemists of our time.

· domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically developed through the chosen synthesis
· cutting edge synthetic technologies are discussed in terms of mechanism and scope
· new reactions, such as olefin metathesis, are presented in mini-review style
· abundant references are given for further reading

Graduate students, educators, and researchers in the fields of synthetic and medicinal chemistry will wish to have a copy of this book in their collection as an indispensable companion that both augments and supplements the original Classics in Total Synthesis.

From reviews of "Classics in Total Synthesis":

"... a volume, (..) which any chemist with an interest in synthetic organic chemistry will wish to acquire."
JACS
"...this superb book (..) will be an essential purchase for many organic chemists."
Nature

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Introduction
Isochrysohermidin (Boger)
Swinholide A (Paterson)
Dynemicin A (Myers)
Ecteinascidin 743 (Corey)
Resiniferatoxin (Wender)
Epothilone A (Nicolaou)
Manzamine A (Winkler/Martin)
Vancomycin (Nicolaou/Evans)
Everninomicin 13,384-1 (Nicolaou)
Bisorbicillinoids (Nicolaou)
Aspidophytine (Corey)
CP-Molecules (Nicolaou)
Colombiasin A (Nicolaou)
Quinine (Stork)
Longithorone A (Shair)
FR-182877 (Sorensen)
Vinblastine (Fukuyama)
Quarigemine C and Psycholeine (Overman)
Diazonamide A (Nicolaou)
Plicamine (Ley)
Abstract in:

Journal of the American Chemistry Society, Vol. 126 No. 14
  • Nicolaou is one of the top synthetic chemists in organic chemistry.
  • Each chapter has a detailed reference section so that each synthetic chemist can find a lot of very important information
  • The Classics II will present completely new and 22 modern total syntheses.
  • Many syntheses are presented which are of great interest for the pharmaceutical industry, like e.g., Vancomycin and Epothilone A.
  • Domino reactions, cascade sequences, biomimetic strategies, and asymmetric catalysis are systematically developed through the chosen synthesis.
  • Cutting edge synthetic technologies are discussed in terms of mechanism and scope.
  • New reactions, such as olefin metathesis, are presented in mini-review style.
  • Abundant references are given for further reading.