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Concepts and Models in Bioinorganic Chemistry

Concepts and Models in Bioinorganic Chemistry

Heinz-Bernhard Kraatz (Editor), Nils Metzler-Nolte (Editor)

ISBN: 978-3-527-31305-1

Jul 2006

469 pages

Select type: Paperback

In Stock



Destined to set the standard, this book meets the need for a didactic textbook focusing on the role of model systems in bioinorganic chemistry. The first part features concepts in bioinorganic chemistry such as electron transfer, medicinal inorganic chemistry, bioorganometallics and metal DNA complexes, while the second part presents inorganic model chemistry on metallo-enzymes, organized by metal ion.
Experts in the pertinent fields provide a didactically well-organized background on relevant biological systems, as well as on their structural, functional and spectroscopic properties. All chapters are similarly structured, each one beginning with a timeline featuring the most important historical facts on the subject, followed by a table of the most significant enzymes. The authors also summarize key developments and open questions within the respective model systems.
This book is aimed at senior undergraduate and graduate students in chemistry, biochemistry, life science and related fields.
The Biodistribution of Metal Ions
Medicinal Inorganic Chemistry
The Chemical Toxicology of Metals and Metalloids
Theoretical Modeling of Redox Processes in Enzymes and Biomimetic Systems
Charge Transport in Biological Molecules
Bioorganometallic Chemistry
The Bioinorganic Side of Nucleic Acid Chemistry: Interactions with Metal Ions
Nuclease and Peptidase Models
Metalloporphyrins, Metalloporphyrinoids, and Model Systems
Model Complexes for Vanadium-Containing Enzymes
Model Complexes for Molybdenum- and Tungsten-Containing Enzymes
Structural and Functional Models for Oxygen-Activating Nonheme Iron Enzymes
Model Chemistry of the Iron-Sulfur Protein Active Sites
Model Complexes of Ni-Containing Enzymes
Hydrogenases and Model Complexes
Model Complexes for Copper-Containing Enzymes
Model Complexes for Zinc-Containing Enzymes
""In summary, I highly recommend this book for graduate students, advanced undergraduate students, and faculty who are interested in gaining insights into many important topics in bioinorganic chemistry. I personally enjoyed reading this book from the first to the last page."" ChemBioChem