Skip to main content

Counseling About Cancer: Strategies for Genetic Counseling, 3rd Edition

E-Book

$64.99

Counseling About Cancer: Strategies for Genetic Counseling, 3rd Edition

Katherine A. Schneider

ISBN: 978-1-118-11991-4 October 2011 Wiley-Blackwell 496 Pages

E-Book
$64.99
Paperback
$81.00
O-Book
Download Product Flyer

Download Product Flyer

Download Product Flyer is to download PDF in new tab. This is a dummy description. Download Product Flyer is to download PDF in new tab. This is a dummy description. Download Product Flyer is to download PDF in new tab. This is a dummy description. Download Product Flyer is to download PDF in new tab. This is a dummy description.

Description

Important scientific discoveries and ever-changing guidelines for how to identify and manage patients with hereditary cancer syndromes are constantly evolving. This Third Edition of Counseling About Cancer is completely updated and expanded to feature five entirely new chapters on breast cancer, colon cancer, other solid tumors, clients and families, and genetic test results and follow-up. This is the only reference and clinical book on the market for cancer genetics counselors and other healthcare providers who must quickly assimilate complex and ever-changing data on the hereditary risk for cancer.

FOREWORD, XI

PREFACE, XIII

ACKNOWLEDGMENTS, XV

CHAPTER 1: CANCER EPIDEMIOLOGY, 1

1.1. CANCER STATISTICS, 1

1.2. CANCER ETIOLOGY, 10

1.3. CASE EXAMPLES, 18

1.4. FURTHER READING, 21

CHAPTER 2: CANCER DETECTION AND TREATMENT, 23

2.1. THE DIAGNOSIS OF CANCER, 23

2.2. TUMOR CLASSIFICATION, 31

2.3. CANCER TREATMENT, 37

2.4. FURTHER READING, 45

CHAPTER 3: CANCER BIOLOGY, 47

3.1. THE MALIGNANT CELL, 47

3.2. CARCINOGENESIS 52

3.3. ONCOGENES, 59

3.4. TUMOR SUPPRESSOR GENES, 64

3.5. EPIGENETIC MECHANISMS, 70

3.6. FURTHER READING, 73

CHAPTER 4: HEREDITARY CANCER SYNDROMES, 75

4.1. ATAXIA TELANGIECTASIA, 75

4.2. AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME (ALSO CANALE–SMITH SYNDROME), 77

4.3. BECKWITH–WIEDEMANN SYNDROME (ALSO EXOMPHALOS MACROGLOSSIA GIGANTISM [EMG] SYNDROME), 78

4.4. BIRT–HOGG–DUBÉ SYNDROME, 80

4.5. BLOOM SYNDROME, 82

4.6. BLUE RUBBER BLEB NEVUS SYNDROME (ALSO TERMED BEAN SYNDROME), 83

4.7. BREAST–OVARIAN CANCER SYNDROME, HEREDITARY, 84

4.8. CARNEY COMPLEX, TYPES I AND II (INCLUDES NAME SYNDROME AND LAMB SYNDROME), 87

4.9. DIAMOND–BLACKFAN ANEMIA, 89

4.10. FAMILIAL ADENOMATOUS POLYPOSIS (ALSO ATTENUATED FAP,GARDNER’S SYNDROME, TURCOT SYNDROME, AND HEREDITARY DESMOID DISEASE), 90

4.11. FANCONI ANEMIA, 93

4.12. GASTRIC CANCER, HEREDITARY DIFFUSE, 95

4.13. GASTROINTESTINAL STROMAL TUMOR, FAMILIAL (ALSO MULTIPLE GI AUTONOMIC NERVE TUMORS), 97

4.14. JUVENILE POLYPOSIS (INCLUDES HEREDITARY MIXED POLYPOSIS), 98

4.15. LEIOMYOMATOSIS RENAL CELL CANCER, HEREDITARY, 100

4.16. LI–FRAUMENI SYNDROME, 101

4.17. LYNCH SYNDROME (ALSO TERMED HNPCC), 105

4.18. MELANOMA, CUTANEOUS MALIGNANT (INCLUDES FAMILIAL ATYPICAL MOLE-MALIGNANT MELANOMA SYNDROME, DYSPLASTIC NEVUS SYNDROME, AND MELANOMA–ASTROCYTOMA SYNDROME), 109

4.19. MULTIPLE ENDOCRINE NEOPLASIA, TYPE 1 (ALSO WERMER SYNDROME), 111

4.20. MULTIPLE ENDOCRINE NEOPLASIA, TYPE 2 (ALSO SIPPLE SYNDROME, FAMILIAL MEDULLARY THYROID CARCINOMA SYNDROME), 113

4.21. MYH-ASSOCIATED POLYPOSIS, 115

4.22. NEUROBLASTOMA, FAMILIAL, 116

4.23. NEUROFIBROMATOSIS, TYPE 1 (ALSO VON RECKLING HAUSEN DISEASE), 118

4.24. NEUROFIBROMATOSIS, TYPE 2, 119

4.25. NEVOID BASAL CELL CARCINOMA SYNDROME (ALSO GORLIN SYNDROME, BASAL CELL NEVUS SYNDROME), 121

4.26. PARAGANGLIOMA–PHEOCHROMOCYTOMA SYNDROME, HEREDITARY (INCLUDING CARNEY–STRATAKIS SYNDROME), 123

4.27. PEUTZ-JEGHERS SYNDROME, 125

4.28. PTEN HAMARTOMA SYNDROME (PHS) (ALSO COWDEN SYNDROME; INCLUDES BANNAYAN–RILEY–RUVALCABA SYNDROME AND PROTEUS SYNDROME), 127

4.29. RENAL CELL CARCINOMA, HEREDITARY PAPILLARY, 130

4.30. RETINOBLASTOMA, HEREDITARY, 131

4.31. ROTHMUND–THOMSON SYNDROME, 133

4.32. TUBEROUS SCLEROSIS COMPLEX (TSC), 134

4.33. VON HIPPEL LINDAU SYNDROME, 137

4.34. WERNER SYNDROME (ALSO TERMED PROGERIA OF THE ADULT), 139

4.35. WILMS TUMOR, FAMILIAL (INCLUDES DENYS-DRASH SYNDROME, FRASIER SYNDROME, WAGR SYNDROME), 141

4.36. XERODERMA PIGMENTOSUM (INCLUDES XP/CS COMPLEX, XP VARIANT), 143

4.37. FURTHER READING, 145

CHAPTER 5: ALL ABOUT BREAST CANCER, 151

5.1. OVERVIEW OF BREAST CANCER, 151

5.2. BREAST CANCER MANAGEMENT: SCREENING, DIAGNOSIS, AND TREATMENT, 162

5.3. BREAST CANCER SYNDROMES, 171

5.4. FURTHER READING, 184

CHAPTER 6: ALL ABOUT COLORECTAL CANCER, 187

6.1. OVERVIEW OF COLORECTAL CANCER, 187

6.2. CRC MANAGEMENT: SCREENING, DIAGNOSIS, AND TREATMENT, 199

6.3. CRC SYNDROMES, 207

6.4. FURTHER READING, 218

CHAPTER 7: COLLECTING AND INTERPRETING CANCER HISTORIES, 221

7.1. COLLECTING A CANCER HISTORY, 221

7.2. CHALLENGES TO COLLECTING AN ACCURATE HISTORY, 242

7.3. INTERPRETING A CANCER HISTORY, 246

7.4. CASE EXAMPLES, 255

7.5. FURTHER READING, 266

CHAPTER 8: CANCER RISK COMMUNICATION, 267

8.1. GENETIC COUNSELING AND RISK PERCEPTION, 267

8.2. THE COMMUNICATION OF RISK, 278

8.3. COUNSELING CLIENTS AT VARIOUS RISKS, 289

8.4. CASE EXAMPLES, 298

8.5. FURTHER READING, 306

CHAPTER 9: GENETIC TESTING AND COUNSELING, 309

9.1. THE LOGISTICS OF ARRANGING TESTS, 309

9.2. PRETEST COUNSELING, 325

9.3. RESULTS DISCLOSURE AND FOLLOW-UP, 337

9.4. CASE EXAMPLES, 346

9.5. FURTHER READING, 356

CHAPTER 10: PSYCHOSOCIAL ASPECTS OF CANCER COUNSELING, 357

10.1. THE PSYCHOSOCIAL FEATURES OF CLIENTS, 357

10.2. MAKING A PSYCHOSOCIAL ASSESSMENT, 379

10.3. PROVIDING ADDITIONAL EMOTIONAL SUPPORT, 394

10.4. CASE EXAMPLES, 400

10.5. FURTHER READING, 407

CHAPTER 11: ETHICAL ISSUES IN CANCER GENETIC COUNSELING, 409

11.1. BIOETHICAL PRINCIPLES AND GUIDELINES, 409

11.2. STRATEGIES FOR RESOLVING ETHICAL DILEMMAS, 423

11.3. TYPES OF ETHICAL DILEMMAS IN CANCER GENETIC COUNSELING, 431

11.4. ISSUES OF JUSTICE, 442

11.5. FURTHER READING, 443

APPENDIX A: SPECIFIC TUMOR TYPES AND ASSOCIATED SYNDROMES, 445

APPENDIX B: REVIEW OF BASIC PEDIGREE SYMBOLS, 457

INDEX, 459