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Crystal Structure Analysis for Chemists and Biologists

Crystal Structure Analysis for Chemists and Biologists

Jenny P. Glusker, Mitchell Lewis, Miriam Rossi

ISBN: 978-0-471-18543-7 October 1994 872 Pages


In Stock



The fields of structural chemistry and biochemistry have blossomed in the last seventy years since X-ray diffraction was discovered in 1912. Dorothy Hodgkin, who obtained a Nobel Prize in 1965 for her X-ray diffraction work wrote 'a great advantage of X-ray analysis as a method of chemical structure analysis is its power to show some totally unexpected and surprising structure with, at the same time, complete certainty.' The results of all X-ray diffraction studies are used by chemists and buiochemists but these scientists need to be able to appreciate the significance and extent to which these results may be used.

A number of books written for practicing crystallographers cover the theory and applications of X-ray diffraction, but few are of real practical use to non-specialists. In 'Crystal Structure Analysis for Biologists and Chemists', the general principles of crystal structure are presented in a highly readable way. The book of Glusker, who is internationally renowned, provides good coverage of theory, including data and understanding their significance.
Introduction to Crystal Structure Analysis/
Diffraction by Crystals/
Symmetry in Crystals and Their Diffraction Patterns/
Physical Properties of Crystals/
Combining Waves to Obtain an Image/
Measurement of Structure Amplitudes/
Estimation of the Phase Angles/
The Electron Density Map/
Least-Squares Refinement of the Structure/
Interpreting x, y, z (Atomic Coordinates)/
Atomic and Molecular Displacements/
Chirality and Absolute Structure/
Packing in Crystals/
Comparisons of Structures/
Recognition and Receptors/
Structure-Activity Results/