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Enzyme Catalysis in Organic Synthesis: A Comprehensive Handbook, 2nd, Completely Revised and Enlarged Edition

Enzyme Catalysis in Organic Synthesis: A Comprehensive Handbook, 2nd, Completely Revised and Enlarged Edition

Karlheinz Drauz (Editor), Herbert Waldmann (Editor)

ISBN: 978-3-527-61826-2

Apr 2008

1596 pages

Select type: O-Book

Description

Organic synthesis with enzymes - the only way

This comprehensive set gives reliable answers to all questions on enzyme catalysis - from searching for suitable catalytic systems via choosing the optimal reaction conditions to implementing modern synthesis strategies. The long-awaited new edition has been greatly expanded to include new topics and to reflect the latest research, yet retains the clear and practice-oriented presentation found in the first edition. More than a mere data collection, the three volumes provide synthetic chemists with easy access to all the first-hand information necessary for successfully using enzymes:
- the latest synthesis methods
- example applications arranged according to reaction type
- a table of all the important, commercially available enzymes
- comprehensive registers for targeted searching according to enzyme, compound, or reaction
- current references to the literature
In short, an indispensable reference that should be on the shelf of every modern synthesis laboratory.
Introduction
Production and Isolation of Enzymes
Rational Design of Functional Proteins
Enzyme Engineering by Directed Evolution
Enzyme Bioinformatics
Immobilization of Enzymes
Reaction Engineering for Enzyme-Catalyzed Biotransformations
Enzymic Conversions in Organic and Other Low-Water-Media
Enzymatic Kinetic Resolution
Enzymes from Extreme Thermophilic and Hyperthermophilic Archaea and Bacteria
Hydrolysis and Formation of C-O Bonds
Hydrolysis and Formation of C-N Bonds
Formation and Cleavage of P-O Bonds
Formation of C-C Bonds
Reduction Reactions
Oxidation Reactions
Isomerizations
Introduction and Removal of Protecting Groups
Replacing Chemical Steps by Biotransformations: Industrial Application and Processes Using Biocatalysis
Tabular Survey of Commercially Available Enzymes
""...an unrivalled wealth of knowledge and experience...destined to become known as 'The Handbook' for biological catalysis in organic chemistry."" (Applied Organometallic Chemistry, Vol.19, No.1, January 2005)