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Derek J. Chadwick (Editor), Gail Cardew (Editor)

ISBN: 978-0-470-51550-1

Sep 2007

238 pages

Select type: O-Book


Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive knowledge of basic transcriptional control as a foundation to explore the more complex and interesting level at which genes can be regulated.
Gene Silencing by Methyl-CpG-Binding Proteins (X. Nan, et al.).

DNA Methylation, Nucleosomes and the Inheritance of Chromatin Structure and Function (S. Kass & A. Wolffe).

Heritable Chromatin States Induced by the Polycomb and Trithorax Group Genes (R. Paro, et al.).

The Dynamics of Globin Gene Expression and Position Effects (F. Grosveld, et al.).

Multiple Epigenetic Events Regulate Mating-Type Switching of Fission Yeast (A. Klar, et al.).

Nuclear Organization and Silencing: Trafficking of Sir Proteins (S. Gasser, et al.).

Epigenetic Mechanisms in the Regulation of the Maize Suppressor=mutator transposon (R. Raina, et al.).

Transgene-Promoted Epigenetic Switches of Chalcone Synthase Activity in Petunia Plants (R. Flavell, et al.).

Gene Silencing in Plants: Relevance for Genome Evolution and the Acquisition of Genomic Methylation Patterns (M. Matzke & A. Matzke).

The Host Defence Function of Genomic Methylation Patterns (T. Bestor).

Mammalian X Chromosome Inactivation (R. Jaenisch, et al.).

Methylation Dynamics, Epigenetic Fidelity and X Chromosome Structure (A. Riggs, et al.).

Imprinting and Gene Silencing in Mice and Drosophila (J. Brenton, et al.).

Making Sense of Imprinting the Mouse and Human IGF2R Loci (A. Wutz, et al.).

Imprinted Genes in the Prader-Willi Deletion (U. Francke).

Summary (A. Wolffe).