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Evidence-Based Paediatric and Adolescent Diabetes



Evidence-Based Paediatric and Adolescent Diabetes

Jeremy Allgrove, Peter Swift, Stephen Greene

ISBN: 978-0-470-69152-6 April 2008 BMJ Books 256 Pages

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Evidence-based Paediatric and Adolescent Diabetes brings together an international group of paediatric diabetes specialists to address the cause, course and complications of all types of diabetes. From a careful review of the latest research, they propose the best possible evidence-based recommendations for the care of children and the youth with diabetes.

The text provides the reader with an understanding across three different levels:

• Reviews how strong the evidence is for recommending one approach over another
• Highlights areas where evidence is not based on the types of studies needed to provide ‘highgrade recommendations’, but where there is a general consensus as to the most sensible approach
• Identifies the issues that remain inadequately addressed such that no definitive recommendations can be made

As the incidence of type 1 diabetes mellitus continues to increase worldwide, and type 2 is being seen in more young people, this timely volume will help a wide range of health care professionals deliver the best possible care to their young patients.

List of contributors.



1 Methodology of evidence-based medicine.

Jeremy Allgrove (Royal London Hospital).

2 Definition, epidemiology and classification of diabetes and structure.

of the diabetes team.

Maria Craig (Institute of Endocrinology & Diabetes), Sarah J. Glastras (Institute of Endocrinology and Diabetes) & Kim Donaghue (The Children's Hospital at Westmead).

3 Aetiology of type 1 diabetes mellitus – genetics, autoimmunity.

and trigger factors.

Loredana Marcovecchio (University of Cambridge), David B. Dunger (University of Cambridge),.

Mark Peakman (King's College London) & Keith W. Taylor (Barts and the London).

4 Type 1 diabetes mellitus – management.

Joanne J. Spinks (John Radcliffe Hospital), Julie A. Edge (John Radcliffe Hospital), Krystyna Matyka (Clinical Sciences Research Institute) & Shital Malik (Paediatric Specialist Registrar).

5 Type 1 diabetes mellitus in the very young child.

Stuart Brink (Tufts University School of Medicine).

6 Adolescence and diabetes: clinical and social science perspectives.

Alexandra Greene (University of Aberdeen) & Stephen Greene (Maternal and Child Health Sciences).

7 Management of special situations in diabetes.

Fergus J. Cameron (Department of Endocrinology and Diabetes) & Jeremy Allgrove (Royal London Hospital).

8 Dietary management: optimising diabetes outcomes.

Sheridan Waldron (Leicestershire Nutrition and Dietetic Service).

9 Education in childhood diabetes.

Peter G.F. Swift (Leicester Royal Infirmary).

10 Psychological interventions in childhood diabetes.

John W. Gregory (Cardiff University) & Sue Channon (Consultant Clinical Psychologist).

11 Screening for associated conditions and prevention of complications.

Catherine Peters (SpR Paediatric Endocrinology) & Jeremy Allgrove (Royal London Hospital).

12 Type 2 diabetes mellitus – genetics, diagnosis and management.

Polycystic ovarian syndrome.

John Porter (Birmingham Children’s Hospital) & Timothy G. Barrett (Institute of Child Health).

13 Rare forms of diabetes.

Julian Shield (University of Bristol), Maciej T. Malecki (Jagiellonian University), Nicola A. Bridges (Chelsea and Westminster Hospital) & Jeremy Allgrove (Royal London Hospital).

14 Diabetes and information technology.

Kenneth J. Robertson (Royal Hospital for Sick Children).



"The purpose is to describe the strength of the evidence underlying many aspects of pediatric diabetes. In addition, it aims to point out areas of management in which strong evidence does not exist, but for which experts have provided a consensus opinion. This worthwhile book provides useful evidence-based information to busy practitioners." (Katherine  J Hladky, MD, @Doody's Review Service)

  • The first evidence-based reference book on the management of children and adolescents with diabetes

  • Covers Type 1 and Type 2 diabetes

  • Addresses issues exclusively relevant to these age groups

  • Includes latest international guidelines

  • Brings together an international group of pediatric diabetologists experienced in evidence-based practice