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Fluorine in Organic Chemistry

Fluorine in Organic Chemistry

Richard D. Chambers

ISBN: 978-1-444-30537-1

Mar 2009, Wiley-Blackwell

424 pages

Select type: O-Book


The introduction of carbon – fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties.

In this new book the author, internationally known for his contribution to organic fluorine chemistry, covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems. Written as an authoritative guide to the subject for organic chemists in universities and the pharmaceutical, agrochemical, specialty organic and polymer industries, the book will also be an important resource for university advanced courses.

Dick Chambers is a Fellow of the Royal Society and Emeritus Professor of Chemistry at the University of Durham, Durham, UK.

General discussion of organic fluorine chemistry; Preparation of highly fluorinated compounds; Partial or selective fluorination; The influence of fluorine of fluorocarbon groups on some reaction centres; Nucleophilic displacement of halogen from fluorocarbon systems; Elimination reactions; Polyfluoroalkanes, polyfluoroalkenes, and derivatives; Functional compounds containing oxygen, sulphur, or nitrogen and their derivatives; Polyfluoroaromatic compounds; Organometallic reagents; References; Index
"In this second, completely revised and enlarged edition, Richard Chambers, a leading expert in the field, brings together everything of importance to fluorine in organic synthesis. With almost 2000 references, this long-awaited revised edition is an indipensible source of high-quality information for everyone working in the filed of fluorine chemistry. More generally, this comprehensive handbook will also prove of great value to all those working in organic chemistry"
Chemistry World<!--end-->

"[This] monograph makes an excellent contribution to the diverse and rich field. [Fluorine in Organic Chemistry] is skillfully crafted to cover various synthetic and mechanistic facets by one of the doyens of the organofluorine chemistry." Richard D. Chambers

"Extensive tables and figures are quite informative and well referenced to the original literature. The author is to be commended for succinctly covering a diverse and interdisciplinary field in a systematic approach."
G. K. Surya Prakash
Loker Hydrocarbon Research Institute and Department of Chemistry, University of Southern California

"[An] essential addition to the library of anyone involved in the field but also to any university library as a standard reference."
Physical Science Education Reviews

* Update of a classic & highly respected book by an internationally renowned author

* Provides a thorough grounding in organic fluorine chemistry for chemists in the pharmaceutical, specialty chemicals and polymer industries

* Key reference source and entry to the literature of fluorine chemistry