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Functions of the Basal Ganglia

Functions of the Basal Ganglia

David Evered (Editor), Maeve O'Connor (Editor)

ISBN: 978-0-470-71858-2

Sep 2009

192 pages

Select type: E-Book



The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Symposium on Functions of the basal ganglia, held at the Ciba Foundation, 22-24 November 1983.

The original suggestion for this symposium came from Professor C. D. Marsden.

Editors: David Evered (Organizer) and Maeve O'Connor.

E. V. Evarts Opening remarks.

W. J. H. Nauta and V. B. Domesick Afferent and efferent relationships of the basal ganglia.


J. P. Bolam Synapses of identified neurons in the neostriatum.


J. M. Deniau and G. Chevalier Synaptic organization of output pathways of the basal ganglia: an electroanatomical approach in the rat.


M. R. DeLong, A. P. Georgopoulos, M. D. Crutcher, S. J. Mitchell, R. T. Richardson and G. E. Alexander Functional organization of the basal ganglia: contributions of single-cell recording studies.


E. V. Evarts and S. P. Wise Basal ganglia outputs and motor control.


General Discussion 1: Basal ganglia links for movement, mood and memory.

The limbic striatum and pallidum.

A. M. Graybiel Neurochemically specified subsystems in the basal ganglia.


J. Glowinski, M. J. Besson and A. Cheramy Role of the thalamus in the bilateral regulation of dopaminergic and GABAergic neurons in the basal ganglia.


C. Reavill, P. Jenner and C. D. Marsden y-Aminobutyric acid and basal ganglia outflow pathways.


General Discussion 2: The striatal mosaic and local control of dopamine.

S. D. Iversen Behavioural effects of manipulation of basal ganglia neurotransmitters.


I. Divac The neostriatum viewed orthogonally.


General Discussion 3: Dopamine depletion and replacement.

Models for basal ganglia disease.

C. D. Marsden Which motor disorder in Parkinson's disease indicates the true motor function of the basal ganglia?


A. M. Wing and E. Miller Basal ganglia lesions and psychological analyses of the control of voluntary movement.


Final general discussion: Local regulation of transmitter release in the basal ganglia.

The subthalamic nucleus.

E. V. Evarts Closing remarks.

Index of contributors.

Subject index.