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Fundamentals of Biochemistry: Life at the Molecular Level, 5th Edition

Fundamentals of Biochemistry: Life at the Molecular Level, 5th Edition

Donald Voet, Judith G. Voet, Charlotte W. Pratt

ISBN: 978-1-118-91846-3

Feb 2016

1152 pages


Voet, Voet and Pratt’s Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future.  While continuing in its tradition of presenting complete and balanced coverage that is clearly written and relevant to human health and disease, Fundamentals of Biochemistry, 5e includes new pedagogy and enhanced visuals that provide a pathway for student learning.


Related Resources

Preface xv

Acknowledgments xix

Guide to Media Resource


1 Introduction to the Chemistry of Life 1

2 Water 23


3 Nucleotides, Nucleic Acids, and Genetic Information 42

4 Amino Acids 80

5 Proteins: Primary Structure 97

6 Proteins: Three-Dimensional Structure 131

7 Protein Function: Myoglobin and Hemoglobin, Muscle Contraction, and Antibodies 180

8 Carbohydrates 221

9 Lipids and Biological Membranes 245

10 Membrane Transport 293


11 Enzymatic Catalysis 322

12 Enzyme Kinetics, Inhibition, and Control 361

13 Biochemical Signaling 402


14 Introduction to Metabolism 442

15 Glucose Catabolism 478

16 Glycogen Metabolism and Gluconeogenesis 523

17 Citric Acid Cycle 558

18 Electron Transport and Oxidative Phosphorylation 588

19 Photosynthesis: Can be found at and in WileyPLUS Learning Space

20 Lipid Metabolism 664

21 Amino Acid Metabolism 718

22 Mammalian Fuel Metabolism: Integration and Regulation 773


23 Nucleotide Metabolism 802

24 Nucleic Acid Structure 831

25 DNA Replication, Repair, and Recombination 879

26 Transcription and RNA Processing 938

27 Protein Synthesis 982

28 Regulation of Gene Expression 1033

Solutions: Can be found at and in WileyPLUS Learning Space Glossary G-1

Index I-1

WileyPLUS Learning Space for Fundamentals of Biochemistry 5e includes:

  • Guided Tours: Students need to visualize processes and recognize the “big picture”. Embedded Guided Toursintegrate visualizations, tutorials   and practice around key concepts.
  • Sample calculation videos: Students come to the course with different levels of math skills. These embedded videos, created by Charlotte Pratt, provide sample calculations and step by step walkthroughs for key equations.
  • Animated process diagrams: Important processes can be stepped through at students’ pace
  • New set of brief Bioinformatics Exercises: short, assessable, and content-specific bioinformatics exercises serve as virtual hands-on assignments that illuminate the connections between theory and applied biochemistry, thereby stimulating student interest and proficiency in the subject.

WileyPLUS Learning Space is an easy way for students to learn, collaborate, and grow. With WileyPLUS Learning Space, students create a personalized study plan, assess progress along the way, and make deeper connections as they interact with the course material and each other. Through a combination of dynamic course materials and visual reports, this collaborative learning environment gives you and your students’ immediate insight into strengths and problem areas in order to focus their time on the weaker areas.