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Fundamentals of Psychoneuroimmunology



Fundamentals of Psychoneuroimmunology

Cai Song, Brian E. Leonard

ISBN: 978-0-470-84236-2 September 2001 294 Pages


Fundamentals of Psychoneuroimmunology Cai Song University of British Columbia, Vancouver, Canada, and Brian E. Leonard National University of Ireland, Galway, Ireland The long-held concept that the nervous, endocrine and immune systems are separate entities has given way to a new understanding of human biology. Psychoneuroimmunology addresses the realisation that the neural, immune, and endocrine systems are inextricably linked and that the effects of each affect all-the systems work together as a complicated set of triggers and balances, an intertwining of the physiological and emotional states. Beginning with the fundamentals of immune and neuroendocrine function, Fundamentals of Psychoneuroimmunology explores the complexities of behavioural assessment, the basic types of immunity, the importance of immune cell redistribution in the response to challenges such as infection and stress, and the multifaceted roles of nerves, hormones and cytokines. This text provides a sound introduction to the field and also serves as a valuable reference to those more familiar with the subject. Fundamentals of Psychoneuroimmunology:
* Is the first book to cover this rapidly growing speciality comprehensively
* Provides a sound biological basis to the discipline
* Covers topics from the biology of immune and neuroendocrine function to the future of psychoneuroimmunology
This volume, by the author of the acclaimed Fundamentals of Psychopharmacology, will be an essential reference for psychiatrists, neurologists, neuroimmunologists, neuroendocrinologists and psychologists, and will, it is hoped, stimulate further exploration into this exciting area of research.
Historical Overview of Mind-Body Interrelationships.


An Outline of Research Methods Used in Psychoneuroimmunology.

Psychoneuroimmunology of Stress.

Stress, the Immune System and Depression.

Immune Abnormalities in Schizophrenia.

Psychoneuroimmunology of Anxiety Disorders.

Polyunsaturated Fatty Acids, the Immune System and Psychiatric Disorders.

Psychoneuroimmunology of Alzheimer's Disease and the Dementias.

Autoimmune Diseases.

The Role of the Thymus Gland in Psychoneuroimmunology.

Animal Models of Stress and Psychiatric Disease and their Potential Application to Psychoimmunology.

Psychoneuroimmunology of HIV Infection and Chronic Fatigue Syndrome.

The Effects of Drugs of Abuse on the Immune System.

Sigma Receptors and the Link Between the Immune and Endocrine Axes.